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I went to my family doctor and fessed up and told him what the situation was, he prescribed the same dosage and bingo: all the ADD problems went away. Like a magnet with iron filing they now lined up.
I search Web MD for Phentermine and ADD: nothing, nada. If you look at the reviews for patients taking Phentermine, they to a person are 4-5 stars. If you look at feed back from other meds for ADD, it is a real marginal return with a lot of bad Juju and few are happy about their meds. I am a member of Mensa, very high on the creative end of the spectrum, and my mind does not seem to stagnate as I get older, but without Phentermine I lose it. I had the most thorough physical of my life and the Doctors reported I am in perfect health with a very strong heart and circulatory system. I am over 65 years old, and I can tell you that ADD does not go away; it is your constant companion and If conquered, a benefit. But it will turn on you in a heartbeat.
My question is why isn't Phentermine prescribed for ADD? What is it is different than straight amphetamines? Why do you get the stimulation without the side affects of Dexedrine. Why is it not a recommended medicine for ADD by the Feds. RTK
Why isn't phentermine prescribed for ADD?
Sometimes it is. Mainly, I think doctors are hesitant to prescribe meds for off-label uses if there's a drug specifically designed to treat a condition. That said, phentermine is being investigated as a potential treatment for ADD so it may be more widely prescribed in the future.
How is it different than amphetamines?
Phentermine works predominately by increasing levels of norepenephrine in the brain. Amphetamines increase the levels of dopamine (predominately). The two neurotransmitters are very similar (one actually converts into the other, I believe) but their effect on alertness/cognition are different.
Why... without side effects...?
There are quite a few side effects associated with Phentermine, including many of the side effects of Dexedrine. However, the difference in mechanism of action probably has something to do with the lower incidence of side effects.
Why not recommended by the feds?
The "feds" rely on research to make recommendations. Since there hasn't yet been much research on the efficacy of phentermine in treating ADD, they can't make any suggestions. Maybe in the future...
Phentermine has been approved as a weight loss medication for the treatment of obesity. It's primary effects are dry mouth and appetite decrease - hence the use in obesity, but it can also increase BO and heart rate. Adderall was initially tested as Obitrol (for weight loss but was not particuarly effective) and brought out again and retested for ADHD.
Everyone with ADHD is not the same and thus have differing involvement of the various neurotransitter systems. It seems that you do better with medications that affect norepinephrine.
Perhaps you shoudl discuss this with your physician and see about one of the non-stimulants like Strattera.
Phentermine works on the hypothalamus portion of the brain to stimulate the adrenal glands to release norepinephrine , a neurotransmitter or chemical messenger that signals a fight-or-flight response , reducing hunger. Phentermine works outside the brain, as well, to release epinephrine or adrenaline, causing fat cells to break down stored fat, but the principal basis of efficacy is hunger-reduction. At clinically relevant doses, phentermine also releases serotonin and dopamine , but to a much lesser extent than that of norepinephrine.[4>
I understand that ADD may be the results of several different causes, so each person will respond differently, but this Phentermine has had the greatest impact on my life. And not for it's intended use.
I dread the day when my prescription runs out and I have to return to the normal ADD fog I have lived with all my life. Until this medication, I did not understand how much of the world I have passed over because of my ability to concentrate and think. It is amazing that I have been able to be as successful as I have with this unseen handicap. It is insulting to have person treat you like you are deliberately trying not to learn or not concentrating. I was punished for this many times in the Navy. Therefore I was also not respected because I was considered slow. However, I did not know that I had ADD.
I hope the FDA will look into allowing Phetermine to be used as an ADD treatment.
Recently, I got a prescription for Phentermine as a weight loss aid. Of course, I don't take the two together.
I was hoping the Phentermine would ease my ADD and help me lose weight.
What I've found is that the Phentermine actually diminishes my concentration ability to a point even lower than when I'm not taking anything.
On the positive side, Phentermine physically motivates me, whereas Adderall is all mental stimulation, keeping me glued to a chair working all day.
I've ditched the Phentermine since it was counterproductive for work and it's appetite suppressing effects were nonexistent for me.
Dopaminergic pathways ORIENT attention. They are NOT exclusively associated with the reward pathways. They are just as much associated with the punishment pathways.
Dopaminergic neurones lock our attention onto the most relevant stimulus in our environment. If that stimulus happens to be a teacher or a boss with a bad attitude- then the results of taking stimulants may not be desirable.
Furthermore, Left brained, analytic attention drives a sympathetic response in and of itself.
Try taking your stimulants and doing a right brained meditation exercise like body scanning or a hypnosis/guided imagery exercise and all those "sympathomimetic" effects will evaporate.
Stimulants are well known to enhance learning in ANY population. If you have access to a legal prescription, then have the sense to use it to train in the most refined and stable attention that you can learn. The schools of thought that teach these attentional skills are thousands of years old, and will probably still be here long after modern psychiatry has been forgotten.
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