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    sweetteyezz posted:
    i'm new to this and hope that someone can help me. my dad is in a nursing home and has alzheimer's, dementia and parkinson's...he's 91 years old. he has been on a low dose of zoloft and seroquil which the doctor has increased in the past 2 weeks. my dad is still very anxious, verbally combative and fighting most of the time. i'm sure he's as frustrated with himself as we are not knowing what to do. of course as caretakers this is taking a big toll on me. can anyone help me?
    cjh1203 responded:
    Hello Sweeteyezz,

    The agitation and aggressiveness your father is exhibiting seem to be pretty common in Alzheimer's patients, but very difficult to treat. I know it's also very difficult for you to see your father in that state.

    Agitation is listed as one of the possible side effects of Zoloft, but that doesn't necessarily mean that it's contributing to the problems your father is having. Seroquel actually is not recommended for dementia patients, but sometimes it's the only medication that can help combat aggressiveness. It can be a case of deciding if the benefits outweigh the risks.

    I imagine your father is taking a lot of medications. You might take a list of them to your pharmacist and see if he/she thinks there might be adverse interactions or reactions making your father's behavior worse, and if there are other drugs that might work better.

    I'm sorry I don't have any better suggestions. It may just be that the doctor needs to up the dosages of the Zoloft and/or Seroquel, or try similar drugs to see if they work better.

    Best wishes.


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