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abilify v seroquel
abby123 posted:
I just took Abilify for 7 weeks and had every side effect - the restlessness was intolerable. Now, my doctor wants me on Seroquel xr. I do feel the depression lifted with the Abilify. What are the diff. bet. AAbilify and Seroquel?
Joseph F Goldberg, MD responded:
Dear Abby123,

Abilify was shown in 2 randomized trials to be the same as a placebo for bipolar depression, but can treat mania or psychosis. It has a somewhat high potential for causing dose-related akathisia (restlessness). Seroquel is FDA approved as an antidepressant for bipolar depression and as an add-on to traditional antidepressants for unipolar depression. Seroquel also treats psychosis and mania, similar to Abilify. It has a higher likelihood of causing sedation and weight gain than Abilify. Both drugs also can raise blood sugar and cholesterol, which needs to be monitored periodically.

Dr. G.
abby123 replied to Joseph F Goldberg, MD's response:
Dear Dr. G. It appears that I have been diagnosed incorrectly and after 14 years with the same psychiatrist board certified at NYU. Now I consider my situation very serious indeed. I am not sure of the next step for me?
Joseph F Goldberg, MD replied to abby123's response:
Dear Abby123,

Treatment decisions depend on many factors. How is your doctor summarizing for you the nature of the current problem, and what recommendations is he or she making?

Dr. G.

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Joseph F. Goldberg, MD, is a Clinical Professor of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY. He also maintains a private prac...More

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