My son is taking 5 mg of saphris 1x at bed, the cherry flavor. He has also been taking depakote but is slowing coming off of the depakote. I think he has responded better to the saphris than the depakote. The small amount seems to work better than the other meds he has tried up to this point (3 years). What is your opinion about taking saphris long term to treat bipolar 1? I have to say that I am very impressed with the results from such a small amount of medication.
Saphris has short-term data for treating mania but no long-term data for preventing mania or depression. The usual standard of care is to have a mood stabilizer, such as Depakote, as the mainstay for relapse prevention, with a therapeutic level. Saphris may be a useful adjunct.
The saphris has helped with the depression, sleep, and psychosis. May will be a year since he's been on it and I have to say that this is the best he's been out of the 3 years since he was diagnosed. He doesn't like taking alot of meds and the saphris seems to work so well with just the one dose so he wanted to stop taking the depakote. I will go to his next appointment and discuss it with his dr.
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