Skip to content


    Attention All WebMD Community Members:

    These message boards are closed to posting. Please head on over to our new WebMD Message Boards to check out and participate in the great conversations taking place:

    Your new WebMD Message Boards are now open!

    Making the move is as easy as 1-2-3.

    1.Head over to this page:

    2.Choose the tag from the drop-down menu that clicks most with you (and add it to any posts you create so others can easily find and sort through posts)

    3. Start posting

    Have questions? Email us anytime at

    Visit our Crisis Assistance Link for resources. For immediate help, get to the ER.

    *No Dr Outside Contact Please*
    Includes Expert Content
    Dr. G - Seroquel and hypoglycemia
    midge6869 posted:
    Dr. G,
    Currently I take Lisinopril, Simvastatin, Naproxen, Omeprazole, Lamictal, Lexapro, and Glipizide ER. Friday night I started taking 100mg of Seroquel for bipolar depression. My morning numbers for blood sugar have always been 130 or higher, even with the Glipizide (my A1C is under 6.0). Since I started the Seroquel, my morning numbers have been in the 80's and I frequently feel hypoglycemic throughout the day. I was wondering if you have heard of Seroquel causing hypoglycemia? Also, do you think I should contact my gp and see about getting the glipizide dosage decreased?
    Thanks again for your help.
    Joseph F Goldberg, MD responded:
    Dear Midge,

    I know of no evidence that Seroquel can cause hypoglycemia. If it had any effect on raising blood sugar, it's usually no more than a few mg/dl and not something one would expect to see within only a few days of starting it. But if your morning fingersticks are running low, that could be unrelated to Seroquel and may be worth discussing with your PCP if it persists...knowing the more likely risk with Seroquel is that it may over time slightly raise blood sugar.

    Dr. G.
    midge6869 replied to Joseph F Goldberg, MD's response:
    Thanks so much !

    Featuring Experts

    Joseph F. Goldberg, MD, is a Clinical Professor of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY. He also maintains a private prac...More

    Helpful Tips

    NSAIDS and lithiumExpert
    Nonsteroidal anti-inflammatory drugs (eg, Motrin/ibuprofen, Advil, Naprosyn) raise lithium levels by about 20%. We often therefore say ... More
    Was this Helpful?
    74 of 98 found this helpful

    Related Drug Reviews

    • Drug Name User Reviews

    Report Problems With Your Medications to the FDA

    FDAYou are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.