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(Dr G) Effect of uncontrolled type 2 diabetes and/or menopause on bipolar 1 disorder
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reneegigliotti posted:
Hi Dr. G,


Can the onset of menopause and/or newly diagnosed uncontrolled type 2 diabetes (HbA1C result of 11.2) exacerbate bipolar 1 disorder symptoms?
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Joseph F Goldberg, MD responded:
Dear Renee,
There isn't a direct correlation between either onset of menopause and bipolar disorder other than (a) menopause can be a risk period for depression in general (bipolar or otherwise) and (b) diabetes creates a stress on your body which is additive to other stresses, including a mood disorder, plus, poorly controlled diabetes may make someone less than an ideal candidate for otherwise effective medicines that can cause weight gain or rising blood sugar. Also, bipolar disorder and diabetes each carry an independent independent increased risk for cardiovascular disease, so the two diagnoses together could exacerbate heart attack risk (and signal the need for minimizing the collective risks for heart disease -- ie, no smoking, weight control, make sure blood pressure is normal, healthy diet and nonsedentary lifestyle, assure LDL cholesterol is well under 130, etc.).

Dr. G.