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Trastuzumab for Recurrent ER Pos patients
montrelblundell posted:
Some recent studies indicate that ER pos, Her2 neg patients with recurrent breast cancer may want to have their breast cancer mets retested for Her2. Many circulating breast cancer cells are turning out to be Her2 positive, making such patients eligible for trastuzumab and other solid her2 targeting therapies. Articles that talk about this: "Her2 and Breast Cancer Stem Cells: More than meets the Eye" in Cancer Research. And "HER2 Status and Benefit from Adjuvant Trastuzumab in Breast Cancer" in the NEJM. And "More Breast Cancer Patients Should Take Herceptin, Studies Hint" in Drug Discovery and Development.
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