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What is your friend's Free T3 thyroid hormone look like? Is it low?
If unbound levels of Tri-iodothyronine (FT3) are low, it can cause elevated lipids, even if TSH is in range. Free T3 is the amount of active thyroid hormone circulating in the blood and available for the body to use.
If levels of FT3 hormone are low, cholesterol could be elevated.
If a person were found to have low levels of active thyroid hormone, taking a combination therapy of T4 and T3 might be beneficial. Typical results would be lower lipids, more energy, and easier weight loss.
An endocrinologist would be the type of doctor that specializes in hormones. This is where I would pursue this requesting a COMPLETE thyroid panel. Not just TSH and FT4.
Bobby
Adding T3 to person who is deficient causes your metabolism to burn brighter and faster, consuming lipids faster.
Hope this analogy helps.
Bobby
Thanks for your response. This is the recent lab report findings:
Cholesterol - 350 mg/dl Very high
Triglyceride - 148.0 mg/dl normal
LDL - 269.4 mg/dl High
HDL - 51.0 mg/dl Normal
VLDL - 29.6 mg/dl
I forgot to mention this
She does take Synthroid 0.1mg Once a day. I read up briefly about this medicine. Am I correct that this only affects TSH (T4?) levels? I'll go and get her reoports from the V.A. next week to see the results. I have a feeling I'll need to take this case out of their hands. Some of our doctors get real "iffy" when we bring in info we have researched and they just shut down on any suggestions. Now he is trying niacin and zetia The thyroid is a complex gland. yes? I'll post later to you to tell you that T3 value and again, thanks for your suggestion/concern
I also remember a hashimoto's case, a man with depression and violent mood swings. Physicians treated him with Synthroid (T4 only) plus anti- depressants. Nothing worked.
A new physician then added T3. He Dropped the anti- depressants. His depression lifted and mood swings vanished. He felt better that he had felt in 20 years.
A healthy human thyroid produces roughly 80% T4, and 20% T3. The body then slowly converts the rest of the T4 into T3
When Hashimotos causes the thyroid to fail, it may fail to produce both T4 and T3. While many folks can get along fine with T4 therapy only, others can't and depend on a combination therapy of both T4 / T3. In rare cases, some individuals take T3 only because that's what works for them.
We are all different. What works best for one person may not work at all for another. I have Hashimoto's myself. I had a severe allergic reaction to Synthroid. Can't take synthroid. However Armour thyroid works great for me, and its drives my cholesterol down lower than I want due to the T3 content.
Keep me posted.
Bobby
If I recall correctly, I saw this on the website of the drugs themselves. Type in the name of a statin drug and go to its official website.
Typical language in the drug literature may look something like this: "Physicians should monitor patients carefully for muscle pain and tenderness if the patient has any of the following conditions..." Then it lists Hypothyroidism as one of the conditions of being at increased risk..
I then researched it and found hypothyroidism is indeed an increased risk for statin induced myopathy for patients with underlying thyroid disorders.
This was years ago. Websites get changed and updated. Wording changes. I would start with the official websites of the drugs themselves, and go the the Physicians Desk Reference online. (PDR)
Example: Use key words Pubmed thyroid hormone cholesterol and you will come up with an articles showing the relationship between cholesterol and thyroid hormone.
http://www.ncbi.nlm.nih.gov/pubmed/12829694
http://www.ncbi.nlm.nih.gov/pubmed/2327707
Statin Associated myopathy hypothyroidism Pubmed
Here we can clearly see hypothyoidism being listed as a higher risk factor for muscle problems associated with statin use.
http://www.ncbi.nlm.nih.gov/pubmed/11758079
Hey, Thanks for the information - this is too cool. I'm looking forward to the research and I appreciate your help in this matter. Have a great New Year Bobby75703 and community.
http://www.medscape.com/viewarticle/726438
http://www.ncbi.nlm.nih.gov/pubmed/19100953
http://www.ncbi.nlm.nih.gov/pubmed/20531048
You must be psychic! - She got 12 capsules 50,000 unit of Vit D in the mail yesterday. No explanation. Everyone in my house doctor is pushing Vit D for various reasons/ailments. Stock must be up in the pharmaceuticals for this stuff. More research. Thanks for the links. A busy weekend looking forward to it.
I have seen reports from some doctors that they give it to their patients that have tested low. But I don't think that it is daily.
Maybe once a week or even once a month.
Maintance dosage is typically 1,000 - 5,000 per day.
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