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Did you mean qid - 4 times a day
or qod - every other day?
In any case that would be a change in dosage and you need to discuss this with your doctor.
You are reducing the dosing by 1/2. Most likely it will reduce the efficacy, but I have no idea by how much.
And I don't know why you want to do this.
If it is for cost Lipitor is now generic and about $15-20/month.
And you can get plain niacin (not the no-flush stuff) very, very cheaply. But it does have different dosing and can be have worse flushing.
If it is because of side effects I know that some doctors do prescribe statins every 2 or 3 days.
I really don't know about the Niaspan, but I suspect that is not practical to change dosing from daily.
You might ask you pharmacist about this and if you want to change then see your doctor.
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