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    Large Study Affirms Safety of Statins
    avatar
    iride6606 posted:
    http://www.medpagetoday.com/Cardiology/Dyslipidemia/40353?xid=nl_mpt_DHE_2013-07-10&utm_content=&utm_medium=email&utm_campaign=DailyHeadlines&utm_source=WC&eun=g511622d0r&userid=511622&email=bryan@ardenthealth.com&mu_id=5634853

    The study included information from 135 randomized trials -- 55 with a placebo control and 80 with an active comparator -- that included a total of 246,955 participants with or without cardiovascular disease. The study initially included trials of atorvastatin, fluvastatin, simvastatin, lovastatin, pravastatin, and rosuvastatin (Crestor); trials of pitavastatin (Livalo) were added post hoc because the protocol was already being finalized at the time the drug was approved.
    In a meta-analysis of trials comparing the statins versus placebo, there were no differences in rates of discontinuation because of adverse events (OR 0.95, 95% CI 0.83-1.08), myalgia (OR 1.07, 95% CI 0.89-1.29), creatine kinase elevations (OR 1.13, 95% CI 0.85-1.51), and cancer (OR 0.96, 95% CI 0.91-1.02).
    Reply
     
    avatar
    Anon_320 responded:
    You're just trying way too hard.
     
    avatar
    iride6606 replied to Anon_320's response:
    I'm sorry, what am I trying way too hard to do? I'm just passing along information as I come across it.


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