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    Available evidence does not support FDA warning linking statin use to cognitive impairment
    iride6606 posted:
    This is just starting to get out, but this finding has been in many discussion in the medical profession over the past few weeks which is now putting pressure on the FDA to remove the statement showing a link on the recent warnings on statins. It is not true and unproven and the FDA looks like they will pull the warning in the upcoming months as they are concerned these hyped up concerns are preventing some from treatment.

    A systematic review of available evidence (low- to moderate-strength) did not find a link between statin use and adverse cognitive outcomes, according to a study published in Annals of Internal Medicine .

    Recently, the FDA issued a warning after case reports suggested that statin use may lead to cognitive impairment. Researchers reviewed 25 published randomized, controlled trials and cohort, case-control, and cross-sectional studies evaluating cognition inpatients taking statins.

    Among statin users, low-quality evidence suggests no increased incidence of Alzheimer disease and no difference in cognitive performance in procedural memory, attention, or motor speed. Moderate-quality evidence suggests no increased incidence of dementia or mild cognitive impairment, nor any changes in cognitive performance.

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