Skip to content
My WebMD Sign In, Sign Up

Announcements

Visit the Cholesterol Management 101 blog.

New US Diet Guidelines: What Not to Eat
Instead of just giving Americans a list of healthy food choices, the federal government takes a stab at showing us what not to eat. Get the facts here.
Last Reply:
High Cholesterol - Can't take a Statin?
avatar
An_188243 posted:
I have very high Cholesterol from genetics - 320 total. I tried two different statins and both elevated my liver enzymes. Diet and Exercise was NOT enough to lower it.

My Doctor then tried me on Fenofibrate and it lowered my Triglycerides by 300 points with out ANY issues with the liver with in 4 weeks.
I'm still waiting on total Cholesterol level results, but you may want to ask your Doctor about Fenofibrate if you can't take a statin.
Was this Helpful?
6 of 10 found this helpful
1 Replies |Report This| Share this:High Cholesterol - Can't take a Statin?I have very high Cholesterol from genetics - 320 total. I tried two different statins and both elevated my liver enzymes. Diet and Exercise was NOT enough to lower it. <br /><br />My Doctor then tried me on Fenofibrate and it lowered my Triglycerides by 300 points with out ANY issues with the liver with in 4 weeks.<br />I'm still waiting on total Cholesterol level results, but you may want to ask your Doctor about Fenofibrate if you can't take a statin.
Reply
 
avatar
toneman84084 responded:
I've been taking Simvastatin along with a Fenofibrate (Tricor) for years, it's a very good drug which works by helping to breakdown fats in your digestive system.

Although they work best of serum TGL's they have been shown to lower LDL in excess of 10% when used along with diet and exercise. The one exception is for people with very high serum TGL's, where they may actually cause an increase in LDL. From the manufacturer;


Fenofibrate can actually cause an increase in LDL cholesterol for people with very high levels of triglycerides (greater than 350 mg/dL). Therefore, the medication should be used with extreme caution or not at all for people with this condition who also have high levels of LDL cholesterol.

Let us know how your numbers turn out.

Tony
Report This| Share this:High Cholesterol - Can't take a Statin?I've been taking Simvastatin along with a Fenofibrate (Tricor) for years, it's a very good drug which works by helping to breakdown fats in your digestive system.<br /> <br />Although they work best of serum TGL's they have been shown to lower LDL in excess of 10% when used along with diet and exercise. The one exception is for people with very high serum TGL's, where they may actually cause an increase in LDL. From the manufacturer;<br /> <br /> <br /><i><b>Fenofibrate can actually cause an increase in LDL cholesterol for people with very high levels of triglycerides (greater than 350 mg/dL). Therefore, the medication should be used with extreme caution or not at all for people with this condition who also have high levels of LDL cholesterol.</b></i> <br /><b><i></i></b> <br />Let us know how your numbers turn out. <br /> <br />Tony
Reply


Back to Top
Back to Top

Featuring Experts

There are no Expert stories for this community right now

Popular Discussions

Start a Discussion | See All

Helpful Tips

Lower Cholesterol by changing my chemical balance - eating habits
With a history of heart disease in my family (father), I was all to aware of the need to keep my numbers under control. A few years ago, I ... More
Was this Helpful?
Yes No
18 of 19 found this helpful
Post a Tip | See All

Helpful Resources

Post a Resource | See All

Related News

Related Drug Reviews

  • Drug Name User Reviews
See More

Report Problems to the
Food and Drug Administration

FDAYou are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.