Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up


All communities will be placed in read-only mode (you will be able to see and search for posts but not start or reply to discussions) as we conduct maintenance. We will make another announcement when posting is re-opened. Thank you for your continued support and patience, and if you have any further questions, please email

Yours in health,
WebMD Community Management

Please take some time to click through these links to find out more about our community.

What is a Trigger and When to Trigger a Post
How and Why to Report a Post
Visit our Crisis Assistance Link for resources. For immediate help, call 911 or get to the ER.

Is depression permanent?
smileygrl8309 posted:
I've been diagnosed w/ atypical depression. I've had it for 6 years now. I know there's no magical happy pill but the meds do help me deal with my unhappiness. I know this because everytime I try to ween off my meds, I get worse. My symptoms are a little different. I also over eat to make me feel better so of course, I'm obese which makes me more depressed. I guess I was hoping someone could tell me that it will get better because they've been where I'm at and survived.Any one with words of wisdom for me? Will I ever be cured??
wiccacelt79 responded:
I have suffered with depression for over 10 years now and I have been on a lot of different meds but nothing really helped. Now I have been taking effexor xr and abilify but I don't notice a change. There have been times when I wanted to give up but so far I am trying to push through. I have gotten discourgaed because I still feel this way. I do wonder if it is permanent.
smileygrl8309 responded:
Merry Meet wiccacelt79!! Thank you so much for answering me! I am now taking Celexa. It seems to be helping but it's only been a week and they usually all do some good when you first change from one to another unless you have bad side effects from the beginning. I try to find pleasure in the little things, like your mail. This was truly a blessing for me. Blessed be.
sunset45 responded:
Depression waxes and wans. Sometimes it is better, then something will happen and you go back down again. Medication helps me so I have been on medication since 1999. However, there have been changes in what I take. Fall and Winter can be hard too with less daylight. I fought the fact that I have depression for a long time, but have finally come to accept it. I know my body now and when I am worse so I know when I need to get in and see my doctor. I keep my appointments too and check in with him every couple of months. It helps keep me on track. I have had talk therapy too for issues I hadn't resolved. I only do that if I need to. Good luck to you. There are worse things out there in the world and worse illnesses. It is a chemical imbalance and not your fault.
happypanda4444 replied to sunset45's response:
am depressed as well, but take zoloft it doesn't work! My psychiatrist won't take me off it!
itmatsb replied to happypanda4444's response:
How long have you been taking the Zoloft. They usually take at least a month to take effect. If it has been that long and your psychiatrist hasn't raised the dose or added anything to it, then you need to find another psychiatrist. Everyone is different with which anti-depressant will help them. Unfortunately it's just a crap shoot as to which one will work, but you definitely need to give each one a real chance. Good luck to you.
itmatsb responded:
To all,
If you have had long term depression which most of you have, you should definitely stay on any anti-depressant that helps you, because otherwise going off and on can make the recovery more difficult and it takes more of the medication to have an effect. In that way, yes depression is a chronic condition that will need life long help. But the newer research shows that not treating it leads to a lot of physical illnesses in much greater frequency.
krazykatt707 responded:
I think for most people it probably is.

Featuring Experts

Thomas L. Schwartz, MD, received his medical degree from and completed his residency in adult psychiatry at the State University of New York (SUNY) Up...More

Helpful Tips

Do not change your meds...Expert
without consulting your prescriber. I am very concerned with many, many posts where folks are dropping, lowering, changing their meds ... More
Was this Helpful?
106 of 144 found this helpful

Related Drug Reviews

  • Drug Name User Reviews

Report Problems With Your Medications to the FDA

FDAYou are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.