Skip to content


    Exciting News for WebMD Members!

    We've been busy behind the scenes building new message boards for you. You'll have new and easier ways to find messages, connect with others, and share your stories.

    And, this will all be available on your smartphone or other mobile device!

    What Do You Need to Do?

    The message board you're used to will be closing in the coming weeks. While many of your boards will be making the move to our new home, your posts will not. Want to keep a discussion going? Save posts you want to continue (this includes your member profile story), so that you can re-post them in the new message boards.

    Keep an eye here and on your email inbox, we'll be back in touch soon to give you all the information you need!

    Yours in health,
    WebMD Message Boards Management

    Please take some time to click through these links to find out more about our community.

    What is a Trigger and When to Trigger a Post
    How and Why to Report a Post
    Visit our Crisis Assistance Link for resources. For immediate help, call 911 or get to the ER.

    How long does Paxil stay in your system?
    bighunter27 posted:
    I am wondering how long Paxil stays in your system after you discontinue use of it?
    susiemargaret responded:
    hello, B --

    the half-life is the amt of a med left in your body after 24 hrs of taking it. after a second 24 hrs, half of that amt would be left (i.e., one-fourth of the original), etc. altho different websites say different things, the consensus (see PS1) seems to be that the half-life of paxil/paroxetine (PS2) is somewhere around 21 hours, with the shortest time being 3 hrs and the longest being 65 hrs and depending whether it is immediate-release or delayed-release. with a half-life of 21 hrs, clearance would ordinarily be within four or five days; however, i have also seen estimates of 5-12 days.

    you might suffer from withdrawal symptoms if you stop all at once, so you need to taper off as slowly as possible instead. i have seen advice that you should reduce your dose as gradually as 5% per week! other sites have said to use "weeks or months," but i've also read that withdrawal can take "only" six weeks. because of this variation, please don't try to stop without talking with your dr first.

    some drs will add a small dose of prozac/fluoxetine (10 mg) to your meds in order to make discontinuation easier; once you are thru with the paxil, it is evidently not hard to withdraw from the prozac.

    i hope this new year is a good one for you.

    -- susie margaret

    PS1 -- i am not a medical person; i welcome, solicit, and indeed beg for correction, amendment, or replacement of inaccuracies in this post.

    PS2 -- webMD info on paxil/paroxetine is at - ORAL.aspx?drugid=6969&drugname=paroxetine HCl Oral&source=2 .
    what good is gold, or silver too, if your heart's not good and true -- hank williams, sr.

    Helpful Tips

    iPhone app that helps me stay active
    I've been using the "Feel Good Tracker" iPhone app to track my activities and to rate how good the activity made me fell. I find that doing ... More
    Was this Helpful?
    4 of 10 found this helpful

    Related Drug Reviews

    • Drug Name User Reviews

    Report Problems With Your Medications to the FDA

    FDAYou are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.