Skip to content
My WebMD Sign In, Sign Up

Announcements

Please take some time to click through these links to find out more about our community.

What is a Trigger and When to Trigger a Post
How and Why to Report a Post
Visit our Crisis Assistance Link for resources. For immediate help, call 911 or get to the ER.


How long does Paxil stay in your system?
avatar
bighunter27 posted:
I am wondering how long Paxil stays in your system after you discontinue use of it?
Reply
 
avatar
susiemargaret responded:
hello, B --

the half-life is the amt of a med left in your body after 24 hrs of taking it. after a second 24 hrs, half of that amt would be left (i.e., one-fourth of the original), etc. altho different websites say different things, the consensus (see PS1) seems to be that the half-life of paxil/paroxetine (PS2) is somewhere around 21 hours, with the shortest time being 3 hrs and the longest being 65 hrs and depending whether it is immediate-release or delayed-release. with a half-life of 21 hrs, clearance would ordinarily be within four or five days; however, i have also seen estimates of 5-12 days.

you might suffer from withdrawal symptoms if you stop all at once, so you need to taper off as slowly as possible instead. i have seen advice that you should reduce your dose as gradually as 5% per week! other sites have said to use "weeks or months," but i've also read that withdrawal can take "only" six weeks. because of this variation, please don't try to stop without talking with your dr first.

some drs will add a small dose of prozac/fluoxetine (10 mg) to your meds in order to make discontinuation easier; once you are thru with the paxil, it is evidently not hard to withdraw from the prozac.

i hope this new year is a good one for you.

-- susie margaret

PS1 -- i am not a medical person; i welcome, solicit, and indeed beg for correction, amendment, or replacement of inaccuracies in this post.

PS2 -- webMD info on paxil/paroxetine is at
http://www.webmd.com/drugs/mono-9095-PAROXETINE - ORAL.aspx?drugid=6969&drugname=paroxetine HCl Oral&source=2 .
what good is gold, or silver too, if your heart's not good and true -- hank williams, sr.


Featuring Experts

Thomas L. Schwartz, MD, received his medical degree from and completed his residency in adult psychiatry at the State University of New York (SUNY) Up...More

Helpful Tips

Ways to help depression
I thought I'd make a little list of things that have helped me, so we can all add to it and help each other. Who knows what we may find, if ... More
Was this Helpful?
27 of 28 found this helpful

Related News

There was an error with this newsfeed

Related Drug Reviews

  • Drug Name User Reviews

Report Problems With Your Medications to the FDA

FDAYou are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.