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Remeron and Wellbutrin
louisesexton posted:
Does anyone have any experience being on a remeron/wellbutrin combination for the treatment of depression? My doctor suggested that I could try this combination if I want. Right now I am just on Remeron. Thanks!
susiemargaret responded:
hello, louise --

according to the interactions checker at,440-203 , remeron/mirtazapine and wellbutrin/bupropion should not be taken together because each of them increases the possibility that you will have a seizure and thus their collective effect makes seizures even more likely (see PS). nonetheless, the recommendation on that website is that if these meds are taken simultaneously, the patient needs to be "monitored closely."

you should know, however, that on several other interactions sites, i found no reference to interactions between these meds. i'm not sure what to think about this inconsistency! if it were me, i would take more seriously the info about the risk of seizures than the info on the sites that show nothing. i am not a medical person, tho.

if you bring up this risk to your dr, i think it would not be wise to say that some woman on the internet said you should not take this combination. you might want to say instead that you learned this info thru your own research, which will be absolutely true if you check out the links i've cited.

i hope this helps.

-- susie margaret

PS -- webMD info on this possibility is at - ORAL.aspx?drugid=13706&drugname=mirtazapine Oral&source=2&dmid=1344&dmtitle=ANTIDEPRESSANTS%2fBUPROPION&intrtype=DRUG&pagenumber=9 and - ORAL.aspx?drugid=13507&drugname=bupropion HCl Oral&source=2&dmid=1344&dmtitle=BUPROPION%2fANTIDEPRESSANTS&intrtype=DRUG&pagenumber=9 . on webMD, the risk of increasing the chance of seizures is characterized as "moderate."
what good is gold, or silver too, if your heart's not good and true -- hank williams, sr.
louisesexton replied to susiemargaret's response:
Thanks for your reply. I think she was just putting it out as an option, but I have been trying to use my skills that I learned when I was in intense dialectical behavioral therapy instead which I would prefer anyway. Also she tends to be a more conservative doctor when it comes to medications.

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