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    Can insulin be absorbed through the skin?
    avatar
    Turvy50 posted:
    My grandbaby's father is Type 1 and asked me if insulin can be absorbed through the skin and I didn't think so, but decided to join this community to see if anyone else knows. Anyone?
    Reply
     
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    nutrijoy responded:
    Topical insulin has been tried experimentally for burn and wound healing "but none have provided convincing evidence as to the safety and efficacy of topical insulin in a clinical situation." Insulin normally will not be absorbed through healthy skin but when applied to open sores and decubitus ulcers, absorption was noted but with unpredictable and inconsistent dosages. So your first assumption as to whether insulin can be absorbed through the skin (for the treatment of diabetes) is no, at least not with current technology.
     
    avatar
    Anon_74671 responded:
    if insulin could be absorbed through the skin, then we wouldn't have to inject it with needles
     
    avatar
    Anon_1092 replied to nutrijoy's response:
    I know there are several companies working on inhaled insulin bbut there are hurdles with the FDA.
     
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    laura2gemini2 replied to Anon_1092's response:
    There used to be an inhaled insulin called "Exubera" made by Pfizer (at least here in the USA, dont know if it was marketed elsewhere). Back in October of 2007 Pfizer stopped production of the medication because of slow sales of the product and not because of any safety issue (so they say).

    From what I remember of the medication, you couldnt use it if you have ever smoked, even as little as 1 cig anytime during your life, nor if you've ever lived with a smoker. It also had the potential of causing some pretty bad breathing issues.

    I did some research and as of right now I didnt see any other manufacturer attempting to create an inhaled insulin mostly because there wasnt really a market for it.
     
    avatar
    Anon_1092 replied to laura2gemini2's response:
    http://www.mannkindcorp.com/product-pipeline-diabetes-afrezza.htm

    This is a company actively working on an inhaled insulin.

    fyi.
     
    avatar
    laura2gemini2 replied to Anon_1092's response:
    Oh well. Can't all be perfect.

    Hopefully they'll have better luck than Pfizer.


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