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    Changing Meds
    FCM1954 posted:
    I recently had to change from Humalog 50-50 to Novalog 25-75. even after having to increase the dosage, the Novalog is not able to control my levels like the Humalog did. Has anyone else had this problem or am I just weird?
    laura2gemini2 responded:
    Well, it may be because the ratio of short to long acting insulin has changed. It used to be with the 50/50 you were getting half short acting and half medium acting insulin. With 25/75 you are getting 3 times the amount of medium acting than short acting.

    Mixed insulins are becoming more of an "old fashioned" way of dosing. Have you though about using a long acting insulin that lasts all day (like lantus or levemir) and a short acting for meals (either humalog, novolog, or apidra)? You have a lot more flexibility with that kind of dosing. The downside is that it is more injections, but it may help you fine tune your sugars.
    auriga1 responded:
    Agree with Laura. BTW, you're not wierd. LOL.

    You should talk with your doctor and tell him/her that this mix of insulin is not working well for you. Above all else, you want your numbers under control.

    Only my opinion, too, that mixed insulins are a bit "old-fashioned." If it's not working, you do need to speak up.

    I take two insulins also, but they are separate injections. I need the basal insulin (Lantus) just to get my numbers under control and keep steady. I take Humalog with meals so that my blood sugar doesn't climb when I eat any carbs. This therapy has been extremely successfuly for me.

    Humalog has a faster start of action time than Novolog, about 10 minutes after injection. Novolog is about 1/2 hour. I don't know if that matters with you.

    Insulin needs change constantly depending on how active you are, your body weight, stress, etc. I have found the more active I am, not just exercising, but active, the less Humalog I need.

    Contact your doctor. Hopefully, they can help you out.

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