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    Amytriptyline- Dr. P
    vinnie02 posted:
    Hi- Been some time since I have posted. My 17 year old has been sick with Mono and I have been taking care of her. Went to see a specialist yesterday and am nervous about the med. he has given her.

    He put her on amytriptyline(sp?). First, it makes me nervous that it is used to treat depression. Mentally my DD is great and I dont want it to affect her in that area. It is 25 mgs. and she is about 158 lbs. How do you feel about this Med. for teens? Before he left he said maybe start at 10 mgs. and go up if needed. But when I picked up the med. it was 25 mgs.

    Not sure there something else I could give her? Or is this what you would prescribe in a similar case? I know you don't know us or her chart, just generally speaking what do you think about this drug? Would you give it to your daughter?
    An_199720 responded:
    Hi Vinnie02,

    I have no expert knowledge about the treatments for mono, but I can let you know my experience.

    My son had mono when he was in elementary school. He was not treated with any medications. As far as I know, there is not a treatment for mono.

    He did have a very enlarged spleen! He could not run, ride a bike, participate in gym, stayed inside during recess,....! This was to prevent his spleen from rupturing.

    Amytriptyline, like any antidepressant, can cause suicidal thoughts expecially in children. This is something you should watch for.

    That's all I know. Hope it helps.
    vinnie02 replied to An_199720's response:
    Hi- That is what I am worried about...There is no treatment for mono but she has been sick since October. They said her mono test came back around 2600...pretty high they said.

    Anyway she has missed about 2-3 days of school a week since then. Low grade fevers, horrible fatigue but not sleeping well at night ( sound familiar to anyone??) Flu like symptoms, achey all over....Been rough for her. Just not sure I want to go this route....Thank's for responding!
    angelswife responded:
    Hi Vinnie,
    My Md prescribed Imipramine 25 mg. (which I haven't taken) for the Fibro. The thought was, if he put me on a low-dose antidepressant I would be able to sleep better and have less pain. To my knowledge there is no treatment for Mono other than rest and vitamin B supplements. But the antidepressants can be used for Fibro.

    Have you thought about having your daughter's vitamin D levels tested? A lot of people with Fibro have low levels; and this may be part of the problem for her as well.

    I can't say yes or no for your daughter; but if you decide to try maybe you can split a pill in half and see how she reacts to a lower dose. (I chose not to take it myself because I was worried about destabilizing my mood; plus I didn't want to deal with the side effects). The one thing to remember with antidepressants, though---once you start them you can't just quit taking them.

    An alternative would be to check out some of the links here, especially the ones for Nutrition and Vitamins. There may be some things there that will help her, especially if you suspect her Mono is actually Fibro. It sounds like you think that may be a possibility. Good luck! :-)
    vinnie02 replied to angelswife's response:
    That is why I have been hesitating as well...I don't want it to change her mentally. I am going to wait and see what her new set of lab's come back like. They are checking vitamun levels,too. Thank you for the info!
    Mark Pellegrino, MD responded:
    Hi Vinnie,

    Amitriptyline is a tricyclic antidepressent medicine that has been used for many years for depression (it's original indication), and, off label, for chronic pain conditions such as peripheral neuropathy and fibromyalgia (based on numerous medical evidence studies)

    I frequently prescribe this medicine in my practice to patients of all ages when I feel it is medically appropriate. The starting dose could be 10mg at bedtime or higher depending on the unique situation of each patient. Like any prescribed medicine, the treating doctor explains the reason for using it, potential benefits and side effects, and answers any questions the patient/guardian may have.

    Please discuss with your son's doctor any specific concerns or questions you may have regarding medicines.

    Dr. P

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