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recurring trichomoniasis
asldka posted:
Third round of meds to treat trichomoniasis that is very persistent and have been dealing with for nearly a year now. The first was a 2 day dose of flagyl, evidently trich did not completely go away and had a 7 day dose of tindamax a couple months later. Now it has recurred again and was prescribed a 10 day dose. On day 2 of the 10 day cycle and the trich has not shown any sign of letting up.
Before taking any meds at all, a GP misdiagnosed the trich as a common yeast infection and "prescribed" a douche. Not knowing any better(though now know douching was a big mistake), this let the trich continue on for several more months without being treated. Is it possible that:
a) douching while having trichomoniasis has caused the infection to become stronger(as douching makes you more susceptible to infection?)
b) the infection is stronger and has built up immunity or what have you to the medication? a gyn suggested this and went on to say that if this were the case, there is pretty much no chance of getting rid of the trich and that the only way to limit the discharge and other symptoms of trich(smell, etc.) was to douche once a week... for ever
this is very hard to deal with and cant help but feel there has to be some other way of treating it. after this 10 day dose of flagyl, there is pretty much no where else to turn according to the gyn. researching on the internet only came up with the 2 solutions that have already been tried, tindamax and flagyl.
the current flagyl cycle is being coupled with acidophilus pills and organic yogurt as sort of homeopathic therapy, per suggestion from the gyn.
Before taking any meds at all, a GP misdiagnosed the trich as a common yeast infection and "prescribed" a douche. Not knowing any better(though now know douching was a big mistake), this let the trich continue on for several more months without being treated. Is it possible that:
a) douching while having trichomoniasis has caused the infection to become stronger(as douching makes you more susceptible to infection?)
b) the infection is stronger and has built up immunity or what have you to the medication? a gyn suggested this and went on to say that if this were the case, there is pretty much no chance of getting rid of the trich and that the only way to limit the discharge and other symptoms of trich(smell, etc.) was to douche once a week... for ever
this is very hard to deal with and cant help but feel there has to be some other way of treating it. after this 10 day dose of flagyl, there is pretty much no where else to turn according to the gyn. researching on the internet only came up with the 2 solutions that have already been tried, tindamax and flagyl.
the current flagyl cycle is being coupled with acidophilus pills and organic yogurt as sort of homeopathic therapy, per suggestion from the gyn.
2 Replies |Watch This Discussion | Report This| Share this:recurring trichomoniasisThird round of meds to treat trichomoniasis that is very persistent and have been dealing with for nearly a year now. The first was a 2 day dose of flagyl, evidently trich did not completely go away and had a 7 day dose of tindamax a couple months later. Now it has recurred again and was prescribed a 10 day dose. On day 2 of the 10 day cycle and the trich has not shown any sign of letting up. <br><br>Before taking any meds at all, a GP misdiagnosed the trich as a common yeast infection and "prescribed" a douche. Not knowing any better(though now know douching was a big mistake), this let the trich continue on for several more months without being treated. Is it possible that: <br><br>a) douching while having trichomoniasis has caused the infection to become stronger(as douching makes you more susceptible to infection?) <br><br>b) the infection is stronger and has built up immunity or what have you to the medication? a gyn suggested this and went on to say that if this were the case, there is pretty much no chance of getting rid of the trich and that the only way to limit the discharge and other symptoms of trich(smell, etc.) was to douche once a week... for ever <img src="http://img.webmd.com/community/images/frown.gif" align="top" border="0"> <br><br>this is very hard to deal with and cant help but feel there has to be some other way of treating it. after this 10 day dose of flagyl, there is pretty much no where else to turn according to the gyn. researching on the internet only came up with the 2 solutions that have already been tried, tindamax and flagyl. <br><br>the current flagyl cycle is being coupled with acidophilus pills and organic yogurt as sort of homeopathic therapy, per suggestion from the gyn.
stephie999 responded:
Hey I feel like I am having the same problem...I know this has been three years ago...but what has the doctor done for you?
Report This| Share this:recurring trichomoniasisHey I feel like I am having the same problem...I know this has been three years ago...but what has the doctor done for you?
Dear stephie: If you have been conclusively diagnosed with recurrent trichomoniasis ("trich") despite several prescription treatments (and partner treatments) you may have a resistant type of trich infection. Here is a very recent citation on this from the National Library of Medicine site:
Sex Transm Dis. 2011 Oct;38(10):983-7.
Utility of antimicrobial susceptibility testing in Trichomonas vaginalis-infected women with clinical treatment failure.
Bosserman EA, Helms DJ, Mosure DJ, Secor WE, Workowski KA.
Source
Atlanta Research & Education Foundation, Atlanta, GA, USA. ebosserman@cdc.gov
Abstract
BACKGROUND:
Antimicrobial resistance is one of the causes of treatment failure in women after standard nitroimidazole therapy for Trichomonas vaginalis infections. The Centers for Disease Control and Prevention provides drug susceptibility testing and guidance for treatment failures but the efficacy of the alternate recommendations has not been assessed.
METHODS:
T. vaginalis isolates from women who had failed at least 2 courses of standard therapy for trichomoniasis were submitted to the Centers for Disease Control and Prevention for susceptibility testing. Alternative treatment recommendations were provided based on in vitro drug susceptibility results and clinical outcomes were collected.
RESULTS:
Drug susceptibility results were available for 175 women tested between January 2002 and January 2008. In vitro, 115 of the 175 isolates demonstrated metronidazole resistance. For all isolates resistant to metronidazole, in vitro resistance to tinidazole was similar or lower. Clinical treatment outcomes were available for 72 women. Of the women receiving an alternative recommended nitroimidazole regimen, 30 (83%) of 36 were cured compared with 8 (57%) of 14 women who received a lower dose than recommended. Clinical and microbiologic success was attained in 59 (82%) of 72 women whose follow-up information was available, with some women requiring multiple treatment courses.
CONCLUSIONS:
Clinical and microbiologic cure rates were higher for women who were treated in accordance with the recommendation provided after in vitro testing compared with those who received a lower dose or a different drug. Susceptibility testing leading to tailored treatment may have a beneficial role for management of women with persistent trichomoniasis.
stephie, the most current 2010 STD Guidelines on trich treatment can be read at this site. Scroll down to the trich section. Please note that consultation and testing services on resistant trich are available to MDs by the Centers for Disease Control (CDC). The phone number for a MD to call is listed at the end of the section.
http://www.cdc.gov/std/treatment/2010/vaginal-discharge.htm#a2
Yours,
Jane
Sex Transm Dis. 2011 Oct;38(10):983-7.
Utility of antimicrobial susceptibility testing in Trichomonas vaginalis-infected women with clinical treatment failure.
Bosserman EA, Helms DJ, Mosure DJ, Secor WE, Workowski KA.
Source
Atlanta Research & Education Foundation, Atlanta, GA, USA. ebosserman@cdc.gov
Abstract
BACKGROUND:
Antimicrobial resistance is one of the causes of treatment failure in women after standard nitroimidazole therapy for Trichomonas vaginalis infections. The Centers for Disease Control and Prevention provides drug susceptibility testing and guidance for treatment failures but the efficacy of the alternate recommendations has not been assessed.
METHODS:
T. vaginalis isolates from women who had failed at least 2 courses of standard therapy for trichomoniasis were submitted to the Centers for Disease Control and Prevention for susceptibility testing. Alternative treatment recommendations were provided based on in vitro drug susceptibility results and clinical outcomes were collected.
RESULTS:
Drug susceptibility results were available for 175 women tested between January 2002 and January 2008. In vitro, 115 of the 175 isolates demonstrated metronidazole resistance. For all isolates resistant to metronidazole, in vitro resistance to tinidazole was similar or lower. Clinical treatment outcomes were available for 72 women. Of the women receiving an alternative recommended nitroimidazole regimen, 30 (83%) of 36 were cured compared with 8 (57%) of 14 women who received a lower dose than recommended. Clinical and microbiologic success was attained in 59 (82%) of 72 women whose follow-up information was available, with some women requiring multiple treatment courses.
CONCLUSIONS:
Clinical and microbiologic cure rates were higher for women who were treated in accordance with the recommendation provided after in vitro testing compared with those who received a lower dose or a different drug. Susceptibility testing leading to tailored treatment may have a beneficial role for management of women with persistent trichomoniasis.
stephie, the most current 2010 STD Guidelines on trich treatment can be read at this site. Scroll down to the trich section. Please note that consultation and testing services on resistant trich are available to MDs by the Centers for Disease Control (CDC). The phone number for a MD to call is listed at the end of the section.
http://www.cdc.gov/std/treatment/2010/vaginal-discharge.htm#a2
Yours,
Jane
Report This| Share this:recurring trichomoniasisDear stephie: If you have been conclusively diagnosed with recurrent trichomoniasis ("trich") despite several prescription treatments (and partner treatments) you may have a resistant type of trich infection. Here is a very recent citation on this from the National Library of Medicine site:<br /><br />Sex Transm Dis. 2011 Oct;38(10):983-7.<br />Utility of antimicrobial susceptibility testing in Trichomonas vaginalis-infected women with clinical treatment failure.<br />Bosserman EA, Helms DJ, Mosure DJ, Secor WE, Workowski KA.<br />Source<br /><br />Atlanta Research & Education Foundation, Atlanta, GA, USA. ebosserman@cdc.gov<br />Abstract<br />BACKGROUND:<br /><br />Antimicrobial resistance is one of the causes of treatment failure in women after standard nitroimidazole therapy for Trichomonas vaginalis infections. The Centers for Disease Control and Prevention provides drug susceptibility testing and guidance for treatment failures but the efficacy of the alternate recommendations has not been assessed.<br />METHODS:<br /><br />T. vaginalis isolates from women who had failed at least 2 courses of standard therapy for trichomoniasis were submitted to the Centers for Disease Control and Prevention for susceptibility testing. Alternative treatment recommendations were provided based on in vitro drug susceptibility results and clinical outcomes were collected.<br />RESULTS:<br /><br />Drug susceptibility results were available for 175 women tested between January 2002 and January 2008. In vitro, 115 of the 175 isolates demonstrated metronidazole resistance. For all isolates resistant to metronidazole, in vitro resistance to tinidazole was similar or lower. Clinical treatment outcomes were available for 72 women. Of the women receiving an alternative recommended nitroimidazole regimen, 30 (83%) of 36 were cured compared with 8 (57%) of 14 women who received a lower dose than recommended. Clinical and microbiologic success was attained in 59 (82%) of 72 women whose follow-up information was available, with some women requiring multiple treatment courses.<br />CONCLUSIONS:<br /><br />Clinical and microbiologic cure rates were higher for women who were treated in accordance with the recommendation provided after in vitro testing compared with those who received a lower dose or a different drug. Susceptibility testing leading to tailored treatment may have a beneficial role for management of women with persistent trichomoniasis.<br /><br />stephie, the most current 2010 STD Guidelines on trich treatment can be read at this site. Scroll down to the trich section. Please note that consultation and testing services on resistant trich are available to MDs by the Centers for Disease Control (CDC). The phone number for a MD to call is listed at the end of the section.<br /><br /><a rel="nofollow" href="http://www.cdc.gov/std/treatment/2010/vaginal-discharge.htm#a2">http://www.cdc.gov/std/treatment/2010/vaginal-discharge.htm#a2</a> <br /><br />Yours,<br />Jane
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