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annony01 posted:
I've just started Yaz, this is my 5th tablet/day. I took birth control pill many yrs ago so can't remember the initial symptoms.


I feel so tired. I also take inderal for migraine prevention which makes me feel tired anyway. How long does it normally take before the initial symptoms wear off? I am struggling to function and feel motivated about anything!
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Jane Harrison Hohner, RN, RNP responded:
Dear annony: You are correct about the sense of fatigue that can be a side effect of beta blockers (eg Inderal). Fatigue is not a common side effect of birth control pills. However, the literature on Yasmin (higher estrogen form of Yaz) states the following:

Beta-blockers (eg, propranolol), corticosteroids (eg, prednisolone), cyclosporine, theophylline, tizanidine, or troleandomycin because the risk of their side effects may be increased by Yasmin.

(from
http://www.drugs.com/cdi/yasmin.html )

For some of the more common side effects (eg nausea) of birth control pills it can take as little as a few days for a symptom to get better. Then sometimes a symptom can get better, then returns briefly when a new pack is started. Overall, most side effects are resolved within a couple of packs. If not then a change to a different brand, or formulation, can be helpful.

In your specific case you may need to monitor the fatigue and if it does not resolve you should return to your GYN. I could not find this drug-drug interaction statement with other formulations of BCPs.

Yours,
Jane


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