Dear An: Thanks for your feedback. It's interesting that "official" tests by the GYN were negative for both yeast and bacterial vaginosis (BV). It was certainly reasonable for you to request STD screenings. If they all come back negative you can cross those off your list of possible causes as well.
Yes, one can develop an inflammation reaction to products used in the vagina. Some common examples would be lubricants, condoms, vaginal washes or vaginal cosmetics, or a new brand of tampon.
By way of overview, a normal discharge is made up from exfoliated vaginal skin cells, bacteria, and secretions from the cervix and vaginal walls. While as many as 30 types of bacteria can be found in normal vaginal discharge, about 95% of a healthy vaginal bacteria population consists of lactobacilli. There are several subtypes of lactobacilli, but the most important type produces hydrogen peroxide. Just like hydrogen peroxide is used to clean cuts and scrapes on the surface of external skin, the hydrogen peroxide produced by the lactobacilli helps decrease the numbers of undesirable bacteria such as E. Coli. A healthy vaginal pH is relatively acidic (pH 3.8-4.5). An acidic pH also discourages undesirable bacteria.
Any change in the balance of "normal" bacteria can change the vaginal ecosystem. Discharge characteristics can vary over a menstrual month depending upon hormones, changes in pH, brief overgrowths of different species of normal vaginal bacteria, and exposure to semen or menstrual flow.
If all your screenings return as negative is it reasonable to do a "watch & wait" to see if the symptoms resolve on their own without further treatment. Sometimes even over the counter treatments can contain ingredients which increase irritation. If symptoms persist or escalate go back to your GYN when the symptoms are the worst for another test.
Yours,
Jane