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    Is this normal?
    An_247894 posted:
    My dr. increased my dosage of Seroquel XR 3 weeks ago, and now my period is 1 wk late? Pregnancy test on Saturday was negative?
    Jane Harrison Hohner, RN, RNP responded:
    Dear An: One of the possible side effects of Seroquel XR is missed menstrual periods. It is also noted that bilateral nipple discharge can also be a side effect.

    Most of the newer medications in this class are supposed to cause less effects on the pituitary gland. The pituitary gland is the source of prolactin (hormone of lactation). An elevated prolactin level can prompt both nipple discharge and interfere with ovulations.

    You did absolutely the right thing in checking for pregnancy first. Now I would urge you to let your psych provider know that you have missed a cycle. Most likely you will be advised to continue on the medication as prescribed as this is a known side effect.

    There are a number of other drugs which have this elevated prolactin effect. I remember seeing a woman referred for rule out menopause. She wasn't menopausal, her newer psych med caused an unanticipated elevated prolactin level.

    Lastly, there are MANY other causes for missing an ovulation and a period including: thyroid problems, ovarian cysts, physical stressors (eg sudden increases in exercise, crash dieting), emotional stressors (problems with boyfriends/girlfriends, money worries), increased body weight, anorexia, rotating shifts at work, etc. Any of these could be the culprit as well.


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