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St. Johns Wort and Hydrochlorothiazide
asis80 posted:
I'm 23 years old and recently have been having spats with high blood pressure. It's mostly of what I eat and a bit of stress. I get into mild mood swings sometimes for no reason and I know I have some slight depression, so a friend suggested St. Johns Wort. My doctor has prescribed me hydrochlorothiazide, but a VERY VERY low dosage. Is this is a lethal combination or should I be ok? I'm going to call my doctor in the morning, just wondering if anyone has any experiences with hypertension medication and St. Johns Wort.

CardiostarUSA1 responded:

"I'm going to call my doctor in the morning"


Generalized note regarding St. John's wort -

This may interact with many medicines, possibly increasing side effects or resulting in decreased therapeutic effects. Do not take St. John's wort without first talking to your doctor.

Take care,


WebMD community member (since 8/99)



Be well-informed

Whole Health MD


St. John's wort

What Is It? Health Benefits. Forms. Dosage. Information. Guidelines for Use. General. Interaction. Possible Side Effects. Cautions. References. Evidence Based Rating Scale. Library&type=AWHN_Supplements&mod=Supplements&mid=&id=21D04512184941B19F8679F8F2259EBA&tier=2

Drug Interaction Checker

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Prescription and over-the-counter drugs may/can interact with other drugs, foods, beverages and dietary supplements.


Good to know, for the primary and secondary prevention of heart attack and brain attack/stroke

Epidemiologic studies (EDS) have revealed risk factors for atherosclerosis (typically affecting the coronary, carotid and peripheral arteries), which includes age, gender, genetics (gene deletion, malfunction, or mutation), diabetes (considered as being the highest risk factor), smoking (includes secondhand), high blood pressure (hypertension), high LDL, high Lp(a), high ApoB, high Lp-PLA2, high triglycerides, LOW HDL (less than 40 mg/dL, an HDL level of 60/65 mg/dL or more is considered protective against dreaded coronary artery disease), high homocysteine, and high C-reactive protein (CRP/hs-CRP).



"Be a questioning patient. Talk to your doctor and ask questions. Studies show that patients who ask the most questions, and are most assertive, get the best results. Be vigilant and speak up!"

- Charles Inlander, People's Medical Society


It's your there. :-) :cool:

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FDAYou are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

For more information, visit the Duke Health General and Consultative Heart Care Center