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apical fixed disease
Pennsyfan01 posted:
could someonr explain apical fixed disease?
cardiostarusa1 responded:

Haven't heard of that term before. Perhaps you are referring to fixed apical defect, as can be sometimes seen on nuclear rest/stress test (stress myocardial perfusion imaging) results.

If so, through the coronary arteries, blood normally flows to/reaches these areas or regions of the heart, e.g., ANTERIOR/ANTERO (front wall), POSTERIOR (back wall), INFERIOR (lower area/lower wall area), APICAL/APEX (bottom tip of the heart) and LATERAL (side wall).

As applicable, a fixed apical defect (scar tissue, irreversible/permanent damage) would indicate no blood flow (no perfusion) to an area there, typically caused by heart attack (myocardial infarction, MI), due to coronary artery disease/atherosclerosis.

ALWAYS be proactive in your health care and treatment. Most important, communicate/interact well with your doctors. Best of luck down the road of life.

Take care,


WebMD community member (since 8/99)




Isotope/Nuclear Stress Test

See: Actual rest/stress nuclear images

The physician can separate a normal left ventricle, from ischemia (live muscle with flow that is compromised only during exercise) and the scar tissue of a heart attack. The distinction is made in the following way:.....

Coronary artery anatomy

Starting with the left anterior descending (LAD) coronary artery, the most critical coronary artery, next to the ultra-critical left main (LM) coronary artery. l



"Be a questioning patient. Talk to your doctor and ask questions. Studies show that patients who ask the most questions, and are most assertive, get the best results. Be vigilant and speak up!"


It's your there.
Pennsyfan01 responded:
Thank you. I was told the defect was in the bottom tip of the heart. Three years ago I was told that I had 30% blockage in two arteries. I have not had a follow up nuclear stress test until this spring because of financial problems. That was when I was told about the fixed apical defect. I was shocked to hear That there was an MI. Again, thank you for clearing this up.

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