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Cholesterol Confusing
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Hopie2008 posted:
I recently had blood work. My total cholesterol was 285, LDL 178, HDL 76 Tri. 156. The doctor called in a cholesterol lowering drug. Within 2 days I felt chest constrictions and total muscle pain over my entire body. My pharmacist told me that I could stop taking this drug which I did. Within 24 hours, I felt normal. I have changed my diet to include low to no cholesterol and low to no fat. I have also tried to incorporate cholesterol lowering foods into my diet such as oatmeal, grains, grape juice, grapes, a glass of red wine, salmon, etc. I have lost 10 pounds. The doctor did not call me in for a consultation----only called in the drug. I am concerned about the side effects as I am also currently taking an antidepressant also--prescribed by the same physician. I hear conflicting information. Some people tell me that my cholesterol is not that high to take a drug, Others tell me that I should not have been given a drug without first trying to lower the cholesterol with diet and exercise.Still others tell me that high cholesterol is genetic and age related and that diet and exercise will not help. I feel that the physician should have called me in for a consultation before prescribing a drug and discuss my risks and options. My insurance will not pay for any more screening until next year. What should I do from here? Presently, I feel great and I am continuing my diet and exercise.
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CardiostarUSA1 responded:
Hi:

I assume that you were taking a statin.

Noteworthy, as reported, advanced blood tests that show the SIZE of one's cholesterol particles can provide detailed info that can help to determine if one should really be on a statin.

Statins are good for some individuals, bad (side effects/adverse reactions) for others. On an individualized case-by-case basis, the benefits of taking a statin must clearly outweigh the risks.

On the positive side, statins may/can stabilize vulnerable plaque (VP).

VP hides well-away within the vessel wall (essentially a 0% blockage, but still unequivocal atherosclerosis), can't even be seen with invasive X-ray angiography, causes no advance warning signs/symptoms, and is now recognized worldwide as the cause of the majority of heart attacks by way of plaque rupture causing a blood clot (thrombus).

Statins also have anti-inflammatory properties and as applicable to the patient, thus lowers C-reactive protein (CRP/hs-CRP). Inflammation is recognized as a major player in the development and progression of atherosclerosis.

Genetics

Suffice to say that sometimes you just can't win (at times, even with prescription drug use).

As applicable, coronary artery disease (CAD) can/does run in some families. One example is a well-known hereditary condition called familial hyperlipidemia or hypercholesterolemia.

Additionally, it has been known for some time now that atherosclerosis actually begins (the process and progression of) at a very early age, even as early as in the pre-teen/teenage years.

Studies performed in the past have shown fatty streaks (represents the earliest precursor to plaque development and plaque is the pathological hallmark of atherosclerosis) as the beginning of atherosclerosis in the coronary arteries. Soft plaque (more dangerous and unpredictable than hard or calcified plaque) is the early stage of atherosclerosis.

ALWAYS be proactive in your health care and treatment. Best of luck down the road of life.

Take care,

CardioStar*

WebMD member (since 8/99)



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Be well-informed

What Your Cholesterol Levels Mean

To determine how your cholesterol levels affect your risk of heart disease, your doctor will also take into account other risk factors such as age, family history, smoking and high blood pressure.

http://www.americanheart.org/presenter.jhtml?identifier=183

Common Misconceptions about Cholesterol

http://www.heart.org/HEARTORG/Conditions/Cholesterol/PreventionTreatmentofHighCholesterol/Common-Misconceptions-about-Cholesterol_UCM_305638_Article.jsp

Readers Digest

Non-Statin Cholesterol Lowering Medications

Othe drugs that can be used alone or in conjunction with statins

http://www.rd.com/health/non-statin-cholesterol-lowering-medications

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KNOW your prescription drugs and KNOW THEM WELL

WebMD

Drugs A-Z

http://www.webmd.com/drugs/index-drugs.aspx

Ask A Patient


Rate a drug, side effects, comments, etc.

http://askapatient.com/rateyourmedicine.htm

iGuard


http://www.iguard.org

Drugstore com

Drug Interaction Checker

Prescription and OTC drugs may interact with other drugs, foods, beverages and dietary supplements.

http://www.drugstore.com/pharmacy/drugchecker

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Quote!

"Be a questioning patient. TALK to your DOCTOR and ASK QUESTIONS. Studies show that patients who ask the most questions, and are most assertive, get the best results. Be vigilant and speak up!"

- Charles Inlander, People's Medical Society
 
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James Beckerman, MD, FACC responded:
I think it's fantastic that you are eating more healthy and are exercising - it really works! Congratulations on your weight loss.

I would tend to think that it makes sense at this time to recheck your numbers in a few months to see what kids of changes you have made. My guess is that your doctor will be happy too and will not recommend medication - especially given your side effects the first go-around. Given that your initial numbers were abnormal, a recheck would not be a screening and will hopefully be covered.


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FDAYou are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

For more information, visit the Duke Health General and Consultative Heart Care Center