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BET105 posted:
2 years ago I went to the ER thought I had a bad case of heartburn...
clogged artery...too deep to operate. Now i take 11 medications.
Whatn are my chances tha t some surgery can correct this/

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cardiostarusa1 responded:

..."too deep to operate."

In general-only here, and beyond drug-therapy, if/when common procedures, first time or re-do, such as angioplasty, with or without stents, or coronary artery bypass graft (CABG) surgey are not deemed feasible, as applicable to the patient, there may/can be other options, that includes non-invasive EECP, laser-based TMR and gene therapy/transfer.

FDA approved non-invasive Enhanced External Counterpulsation (EECP) treatments.

Are You a Candidate for EECP Therapy?

Surgical-based transmyocardial revascularization (TMR, FDA approved).

Holmium:YAG laser

Growing your own so-called "bio-bypass" (collateral vessels) around blockages in the heart, and in the legs
It's known as gene therapy/gene transfer, which has been in experimental phases for quite some time now.
As reported, over the last 20 years, gene therapy has moved from pre-clinical animal investigations (animal models) to human clinical studies for many diseases ranging from single gene disorders, to much more complex, multi-factorial, multi-conditional diseases such as dreaded cancer and cardiovascular disorders.

Readers Digest Online - February 2008

An experimental treatment is giving desperately ill heart patients a new lease on life.

A process called angiogenesis. The experimental procedure had shown great promise in two German studies, and the FDA had approved the launch of the first American clinical trial.

The technique involves injecting the heart with a protein called fibroblast growth factor 1 (FGF-1).

"The protein is like a seed that causes new vessels to sprout, creating a network of capillaries and small arteries."
FGF-1 occurs naturally in the body.

The bottom line

Coronary artery disease (CAD) is a life-long unpredictable condition (can exhibit periods of stabilization, acceleration, and even some regression), requiring a continuum of care.

Best of luck down the road of life.

Take care,


WebMD member (since 8/99)



Be well-informed


Living with Coronary Artery Disease (CAD)

CAD is a chronic disease with no cure. When you have coronary artery disease, it is important to take care of your....

This is especially true if you have had an interventional procedure or......

Recognize the symptoms...

Reduce your risk factors...

Take your medications...

See your doctor for regular check-ups...

Coronary artery anatomy

Starting with the LAD, the most critical, next to the ultra-critical LM.


Good to know, for the primary/secondary prevention of heart attack/brain attack

Epidemiologic studies have revealed risk factors (encompasses some new, novel or emerging) for atherosclerosis, typically affecting carotid, coronary and peripheral arteries, which includes age, gender, genetics (gene deletion, malfunction or mutation) , diabetes, smoking (includes second and thirdhand), inactivity, obesity (a global epidemic, "globesity"), high blood pressure (hypertension), Low HDL (now questionable, according to recent studies) high LDL, small, dense LDL, RLP (remnant lipoprotein), high Lp(a), high ApoB, high Lp-PLA2, high triglycerides, HDL2b, high homocysteine (now questionable), and high C-reactive protein (CRP/hs-CRP).


The hospital/medical center you choose can make a difference...a critical difference. Choose wisely!

Credentials, Experience, Research

U.S. News & World Report

Best Hospitals: Heart & Heart Surgery



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FDAYou are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

For more information, visit the Duke Health General and Consultative Heart Care Center