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    Warfarin medication problems.
    whatitis posted:
    Has anyone had any issues related to taking Warfarin in regards to the medication strength not being what is should? A family member has been having issues with it & so am I now. The strength that the pills say they are, seem much lower. Is there some place I can take a sample of their & mine (warfarin tablets) to have them checked? We are both having INR issues & we get our medication from different places. My family member was the first to think something is wrong since they are not able to maintain their INR level. Within the last two months, I am now having the same issue after being on this for 20 plus years with no problems. I was told that since this is a generic drug the measure is not as refined. But I have been on Warfarin for a very long time. I think the strength is compromised. I really want to get the pill tested. Where can I do that? Help please, as this has become a very serious issue for me now.
    cardiostarusa1 responded:

    "The strength that the pills say they are, seem much lower."

    "I think the strength is compromised."

    Be sure to contact the manufacturer of the drug.

    For those on Coumadin/warfarin therapy, as reported, it is best to manage this narrow therapeutic index drug according to the International Normalized Ratio (INR) guidelines.

    For most clinical conditions/situations, an INR of 2.0/2.5 to 3.0 indicates the appropriate dosage. An INR above 5.0 can be dangerous. An INR of 1.0 indicates no Coumadin/warfarin effect/benefit at all.

    The best way to maintain a proper (appropriate for one's specific condition) INR Coumadin/warfarin level is to basically keep one's diet (food, which includes those that contain vtamin K, and beverages), prescription drug-therapy, etc., the same from day-to-day.

    As applicable, a change/changes in metabolism (or other factors and conditions) can sometimes be responsible for fluctuating/different levels of Coumadin/warfarin.

    Patient resources / Be well-informed

    Cleveland Clinic

    Understanding Coumadin




    _ . _

    Special WARNINGS about Coumadin (warfarin)

    Treatment with so-called blood thinners (it actually does not do that) may increase the risk that fatty plaque will break away from the wall of an artery and lodge at another point, causing the blockage of a blood vessel. If noticing any of the following symptoms, contact your doctor immediately -

    Abdominal pain; abrupt and intense pain in the leg, foot, or toes, blood in the urine, bluish mottling of the skin of the legs and hands, foot ulcers, gangrene, high blood pressure (hypertension), muscle pain, purple toes, rash, or thigh or back pain.

    _ . _

    Best of luck down the road of life.

    Take care,


    WebMD member (since 8/99)




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