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Warfarin and gout
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radioman720 posted:
I have recently been treated for blood clots in my leg and for pulmonary embolisms. I was on IV treatment Heparin and am taking warfarin (currently 11 mg.). We are working on getting the dosage theraputic. I was released with an INR of 2.6 and 48 hours later it was 4.4. I also take Avalide (anti-hypertensive med with diuretic) daily. I have a sore heel that feels like pain I had with previous incidents of gout. Does the combination of these medications have anything to do with a higher chance of gout? I also have a family history of both blood clots and gout. My father suffered from both and took coumadin as long as I can remember.
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CardiostarUSA1 responded:
Hi:

"Does the combination of these medications have anything to do with a higher chance of gout?"

In some individuals (as reported in various medical literature), it may/can.

Also, as reported, gout develops more frequently in males than in females, and is more common in adults. Those with Type 2 diabetes, obesity, sickle cell anemia, and kidney (renal) disease have an increased risk of developing gout.

Drugs such as cyclosporine, thiazide diuretics (so-called "water pills"), and salicylates (aspirin, ASA) can interfere with uric acid excretion, as can excessive alcohol consumption. In rare instances, one may inherit a decreased ability to metabolize purines, thus having an increased tendency to develop gout.

Most important, communicate/interact well with your doctors. Best of luck down the road of life.

Take care,

CardioStar☆

WebMD community member (8/99)

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☑Be well-informed

American College of Rheumatology

GOUT

What causes gout?

www.rheumatology.org/public/factsheets/diseases_and_conditions/gout.asp

Ezine articles

Are the Drugs You Take Causing Your Gout Attacks?

ezinearticles.com/?Are-the-Drugs-You-Take-Causing-Your-Gout-Attacks?&id=1892625

☞Healthwise Brief

Increase in uric acid - Gout

Causes

Medicines include some diuretics, vitamin C (ascorbic acid), lower doses of aspirin (75 to 100 mg daily), niacin, warfarin/Coumadin, cyclosporine, levodopa, tacrolimus, and some medicines used to treat leukemia, lymphoma, or tuberculosis.

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It's your future......be there.

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☛WebMD/WebMD message boards does not provide medical advice, diagnosis, or treatment.


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