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Warfarin and gout
radioman720 posted:
I have recently been treated for blood clots in my leg and for pulmonary embolisms. I was on IV treatment Heparin and am taking warfarin (currently 11 mg.). We are working on getting the dosage theraputic. I was released with an INR of 2.6 and 48 hours later it was 4.4. I also take Avalide (anti-hypertensive med with diuretic) daily. I have a sore heel that feels like pain I had with previous incidents of gout. Does the combination of these medications have anything to do with a higher chance of gout? I also have a family history of both blood clots and gout. My father suffered from both and took coumadin as long as I can remember.
CardiostarUSA1 responded:
Hi: b "Does the combination of these medications have anything to do with a higher chance of gout?" In some individuals (as reported in various medical literature), it may/can. Also, as reported, gout develops more frequently in males than in females, and is more common in adults. Those with Type 2 diabetes, obesity, sickle cell anemia, and kidney (renal) disease have an increased risk of developing gout. Drugs such as cyclosporine, thiazide diuretics (so-called "water pills"), and salicylates (aspirin, ASA) can interfere with uric acid excretion, as can excessive alcohol consumption. In rare instances, one may inherit a decreased ability to metabolize purines, thus having an increased tendency to develop gout. Most important, communicate/interact well with your doctors. Best of luck down the road of life. Take care, CardioStar☆ WebMD community member (8/99) - - b ☑Be well-informed American College of Rheumatology b GOUT What causes gout? Ezine articles b Are the Drugs You Take Causing Your Gout Attacks? ☞Healthwise Brief b Increase in uric acid - Gout Causes Medicines include some diuretics, vitamin C (ascorbic acid), lower doses of aspirin (75 to 100 mg daily), niacin, warfarin/Coumadin, cyclosporine, levodopa, tacrolimus, and some medicines used to treat leukemia, lymphoma, or tuberculosis. . It's your there. :-) . . b ☛WebMD/WebMD message boards does not provide medical advice, diagnosis, or treatment.

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