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Key to Healthy Arteries
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DeadManWalking56 posted:
Endothelial Progenitor Cells

One of the body's natural stem cell varieties, EPCs repair arteries and keep them healthy. But things we do and eat can interfere with their function and how many are circulating, making arterial damage more prevalent and more difficult to recover from.

I've found many articles on Pubmed with good information on EPCs. The goals: Increase number of circulating EPCs, and improve their function. A summary:

http://www.ncbi.nlm.nih.gov/pubmed/19013573
- veggies, higher potassium and magnesium

http://www.ncbi.nlm.nih.gov/pubmed/18925614
- thiamine, especially with diabetics

http://www.ncbi.nlm.nih.gov/pubmed/18627346
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1. http://www.ncbi.nlm.nih.gov/pubmed/19587603?ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_SingleItemSupl.Pubmed_Discovery_RA&linkpos=1&log$=relatedarticles&logdbfrom=pubmed

2. http://www.ncbi.nlm.nih.gov/pubmed/16770559
- habitual exercise boosts EPC effects (good)

http://www.ncbi.nlm.nih.gov/pubmed/18766198
- EPC reduced by homocysteine (Hcy).
- B vitamins lower Homocysteine (good), and help maintain EPC count (good)

http://www.ncbi.nlm.nih.gov/pubmed/19706393
- low carb, high protein diet reduces EPCs (bad)

http://www.ncbi.nlm.nih.gov/pubmed/16322535
- all Cardiovascular disease risk factors lower EPCs, reduce endothelial health, compounding risk of arterial disease. As you cease or stop various heart disease risk factors, your arteries can heal more quickly. (very good)

http://www.ncbi.nlm.nih.gov/pubmed/18627346
http://www.ncbi.nlm.nih.gov/pubmed/15478946
- oxidized-LDL reduces EPC counts, and inhibits EPC activity (very bad)

http://www.ncbi.nlm.nih.gov/pubmed/15099190
- EPC counts and their functional activity correlate inversely to LDL and total cholesterol counts. As your LDL and total cholesterol come down, EPCs work better. (very good)
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DeadManWalking56 responded:
I wrote this as part of another discussion,and felt it gave a really good summary.

Not many foods have been isolated as boosting EPCs directly, but they can be assisted pretty easily with good will power. Its amazing that with each reduction or elimination of a lifestyle risk factor for heart disease, EPCs are increased and function better to heal and protect the arteries. Its like "hiking" with a backpack so heavy that it requires you to crawl on the ground. As you lighten the load, you discover you can do more than barely move, then you can actually crawl, then you can finally stand, start to discern a pace, then begin to walk, and to run, and to be able to play.

Paraoxonases' functions in reversal of athersoclerosis are equally impressive. Green tea also seems to boost it, as does ... OLIVE OIL. Even better, an olive oil with a green tea extract was more effective at boosting paraoxonase. That is in another tip or resource I have posted. Perhaps just olive oil on the salad with green tea on the side as a beverage has the same effect.

Atherosclerosis reversal is a slow process. Fuhrman's studies noted an average of 5% a year, but that was without any focus on increased paraoxonase. But with paraoxonase as the major active factor for reversal, besides the passive factors of other lifestyle risk reductions, it may be much faster than 5% a year. We all hope so. Turbocharging HDL for LDL removal, an anti-oxidant boost, plus stimulating ox-LDL expulsion from blockage foam cells are individually pretty amazing results for a small dietary change.

Pomegranates are actually written about in the Bible, and have been and still are very popular in the Middle East. A co-worker has told me of families splitting an 8-inch pomegranate as dessert for an entire family. They seem to be perhaps one of the most critical fruits on the planet to eat for good health and to preserve the heart. Now we know at least one major function in what they do for health. Talk about a gift from Heaven.

DMW


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