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Sugar suppresses the immune system
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engineerguy posted:
Hi folks,

Sugar suppresses the immune system. If you are thinking you may come down with a cold, etc, avoid sugar. Or, try an experiment. Eat lots of sweets, and see if it doesn't get worse. Fun !


This study was designed to test a) whether carbohydrates other than glucose decreased the phagocytic capacity of neutrophils (a type of white blood cells) in normal human subjects, b) the duration of this effect, and c) the effect of fasting on neutrophilic phagocytosis (eat and kill bacteria). Venous blood was drawn from the arm after an overnight fast and at 0.5, 1, 2, 3, or 5 hr postprandial and this was incubated with a suspension of Staphylococcus epidermidis. The phagocytic index (mean number of bacteria viewed within each neutrophil) was determined by microscopic examination of slides prepared with Wright's stain. Oral 100-g portions of carbohydrate from glucose, fructose, sucrose, honey, or orange juice all significantly decreased the capacity of neutrophils to engulf bacteria as measured by the slide technique. Starch ingestion did not have this effect. The decrease in phagocytic index was rapid following the ingestion of simple carbohydrates. The greatest effects occurred between 1 and 2 hr postprandial, but the values were still significantly (about 43%) below the fasting control values 5 hr after feeding (P < 0.001). The decreased phagocytic index was not significantly associated with the number of neutrophils. These data suggest that the function and not the number of phagocytes was altered by ingestion of sugars. This implicates glucose and other simple carbohydrates in the control of phagocytosis and shows that the effects last for at least 5 hr. On the other hand, a fast of 36 or 60 hr significantly increased (P < 0.001) the phagocytic index.

Free full text: http://ajcn.nutrition.org/content/26/11/1180.full.pdf+html

Best regards, EngineerGuy (Stacy)
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