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What can cause a Hepitis B false positive?
elizabetht7 posted:
Hi. I've been donating plasma for about 6 or 7 months now, and when I went in last night, I was told that I've been deferred because my last draw tested positive for Hepatitis B. The nurse went back through my charts, and every other time they've tested me, I've been clean (including the prior week).

I don't do drugs, I haven't had sex in over 7 years, and I haven't been exposed to blood or anything (at least that I know of), so if it is true, I don't know how that can happen. The nurse did think it was a false positive, but unfortunately, I'm deferred.

I'm going to get tested this week to make sure, but in the meantime, what can cause a false positive? I haven't been able to find that info online. And if I do come out clean, is there any way to get undeferred that you all know of? From what I can see online, it looks like no, but that seems really messed up that if someone really is clean, they can never donate plasma or blood again and this lingers after them.

Anyway, thanks in advance.
Melissa Palmer, MD responded:
It is difficult to tell without knowing exactly what they found abnormal. If it was a hepatitid B core antibody HBcAb this was either
1. A false positive - in which case you would not be able to donate blood again
2. You were exposed and need to have a hepatitis B surface antigen and hepatitis B DNA checked to see if you have chronic disease and if you are contagious

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