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    RibaPak instead of ribavirin trends to an increased cure rate of HCV
    avatar
    Melissa Palmer, MD posted:
    Adherence to pegylated interferon (PIFN) plus ribavirin (RBV), especially in the first 12 weeks, affects sustained virologic response (SVR) in patients with chronic hepatitis C virus (HCV). RibaPak? (RBP) requires fewer tablets than RBV.
    Aim: To determine if simplifying the dosing regimen of RBV impacts outcomes.
    Methods: Ninety-two patients on RBP >12 weeks were categorized as follows: Group A
    (n = 22): treatment experienced with IFN/PIFN and RBV, Group B (n = 49): treatment
    na?ve switched to RBP after >12 weeks RBV, Group C (n = 21): treatment na?ve on
    RBP. Outcomes were compared between RBP and RBV in Groups A and B. Group C
    was compared to Group D—a matched control group of RBV-treated patients.
    Results: Patients preferred RBP. RBP was associated with improved patient compliance,
    less side effects, improved quality of life and a trend toward improved SVR.
    Conclusions: RibaPak offers an attractive alternative to RBV.RibaPak blister packs offer an attractive alternative to traditional RBV bottled pills.
    Patients prefer RibaPak compared to RBV due to
    decreased number of pills, convenience of the blister
    pack administration, diminished side effects (primarily
    GI) and improved quality of life. RibaPak is associated with
    improved patient compliance compared to RBV. This
    has the potential to avoid wasted drug costs and reduce
    future comorbidity that is associated with significant
    health care expense. As the future of HCV treatment
    will likely involve the addition of a third drug (such as
    a polymerase or protease inhibitor), simplification of
    the treatment regimen by a reduction in the number of
    pills may be crucial to treatment success.
    Was this Helpful?
    13 of 19 found this helpful
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    oldtiff47 responded:
    10 YEARS AGO MY RIBA CAME IN PACK AND HAD TO CUT IT OUT OF THEM.....NO ONE COULD POP THEM OUT....IT WAS SO FUNNY THEN...

    TIFF
    DON'T TAKE YOUR ORGANS TO HEAVEN...HEAVEN KNOWS WE NEED THEM HERE !!


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