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    Spike in Blood Pressure
    nancylien posted:
    My boyfriend, age 57, in excellent physical shape, has been taking toporl xl for approx 2 years. It works to keep his bp within range, but recently the meds were replaced by a metropol without the time release to be taken twice per day. This caused his bp to rise (but not dangerously). Two weeks ago we began a strict low sodium DASH diet, following the portions and meal plans to the letter. Shortly after he began taking the toporol xl's again when they were available and still maintaining the DASH diet he experienced a big jump in bp readings off the home machine, up to 250/100. After he went for a walk and sat down for awhile it came to about 140/90 or so. He is also taking fish oil tablets and a daily dose of a concentrated fruit/vegie powder (CQ-10?)in smoothies. What could be causing this alarming spike in his bp? The DASH book said that this diet was known to reduce bp substantially even without medication. :neutral:
    nancylien responded:
    There was a typo, the reading went to 205/100. Pretty high.
    sjayc responded:
    I don't know if anyone else has experienced this but both my wife and I have had our BP go up after taking antihystamines for a period of time Allegra and Claritin. Her doctor was concerned and told her to use my BP machine twice a day and keep track of it. She had always had pretty low blood pressure. After we quit the antihystamines our BP returned to much lower levels. Today: 104/64 sjayc
    run2bhealthy4life responded:
    Hmm... since both medications were beta blockers I doubt changing meds was the problem. However, beta blockers as a whole are known to have significant side effects, so much so that the UK only uses them if absolutely nothing else has worked. They also mess with your body's ability to regulate temperature and are notorious for having negative effects on your ability to exercise. The American College of Sports Medicine wrote a great guide which covers the implications of exercise and hypertension medications, among other topics. You can find it at The spike could have also been due to other factors. Did he have anything stressful happen in his life- like a death, car accident or financial crisis? Did he begin taking any medications with a decongestant? Did he start an ibuprofen regimen? Start thinking about what else changed when he had his spike and you will probably find the cause. Good Luck! P.S. The DASH diet really does work- hang in there!
    ken1047 responded:
    Blood pressure readings can vary quite a bit. You want to make sure you sit quietly without noise or distractions for 5 minutes before taking a reading. Then you may want to stay seated and take 1-2 more readings a few minutes later . Sometimes, I find that mine will drop 10 or more points doing that. Try to avoid taking in an agitated/tense situation. If you are consistently getting the high readings, then you may have an issue. Just worrying about the BP can make it rise. I doubt it is the diet, unless it is causing stress or less sleep due to the change. It can take a few weeks for a medication to be fully effective. So, it could be the switch back is causing an issue. Stick with it for a few more weeks, try to take calm readings and see what happens. Other medications (advil, antihistamines) can also cause an increase, so make sure that is not the cause.
    Loveingit responded:
    I am also taking metropol as well when I first started I had a increase in BP as well. How many mg does he take twice a day.
    M94Laina responded:
    I recently had a severe spike in blood pressure that was very frustrating. After being referred to a kidney specialist I found out that the advil I had been taking for a pulled tooth was the cause. I couldn't believe it! There are so many things that can cause spikes, just try to relax and figure it out what your trigger could be. Good Luck!!
    billnewnan responded:
    the problem, i think, is with toprol itself. i was on it for years and had nothing but problems with it. I knew i wasn't nuts when i googled 'toprol s@#$s'...just read the message boards. this stuff is dangerous.
    ybonniy responded:
    nancylien, I have had hypertension for approx. 15years. It has been well controlled on lisinopril which is an ACE inhibator and according to my kidney doctor the easiest of the hypertensive meds on the kidney. Over the past year I have experienced a number of spikes in my B/P. I had as many tests as could be done trying to find the cause but nothing could be detected. These spikes occur for as long as a month at a time. Recently I had a spike that was life threatening and had to make an emergency trip to my cardiologist. At the time I had been taking cardizem for pain in my chest under my heart that has been for many years attributed by the cardiologist to my mitral valve prolapse. The doctor increase my cardizem to 2 tabs 30mg three times a day instead of one tab three times a day. I had already increase my lisinopril to 40 mg from 20mg as the spike continued after one week. I took the meds as prescribed by the cardioligst including continuing the lisinopril at 40 mg. Within a week after starting this regiem my blood pressure dropped to 85/45 range. First I stopped taking one cardizem a day (30mg) which did noting for my hypotension and symptoms of hypotension. like geting dizzy when I stood up to fast. I then after a week dropped another 30mg which did noting again to bring my blood pressure up. I then went back to taking 1 cardizem 3 times at day. But I still suffered from hypotension. I waited approx 3 weeks and them had to drop my lisinopril to 20mg per day. Currently I have had to monitor my blood pressure 2 times a day. I had finally come up to 107/67. I wanted a more normal blood pressure of 115/ 75 range, so yesterday I did not take my lisinopril until I took my second b/p pressure of the day which was 130/92. The next day I took my first b/p in the morning shortly after awaking so I would be relaxed but sat up with both feet on the floor and my arm a heart level. My b/p and it was 131/82. I took my regular drug dosage of 20mg of lisinopril and 30 mg of cardizem.At the present time my bp is 105/64. I guess I will just have to settle for thisbp. But I also know that low pressue can also affect your kidneys not as dramaticly as high bp. I just want my kidneys to work for the rest of my life. I 'll just stay on this medication regieme until the next spike. By the way there is nothing that I do that relates to the spike. I continued to have extreme hypertension in the doctors office. I t did not go down until I went home and took a cardizem so my spikes are well documented in my mediccal histroy. I also take an omega 3 suppliment, I take a high iron mulitvit, a sublingual vit 12, folic acid and b6 vit. (sl because it is suppose to increase the absorption of the b12 as very little is absorbed by the gut), and I take a suppliment called acai (pronouned acieeee) for the best possible antioxidents in my diet. I am on other meds but none that affect my bp. Waiting for the next spike unless someone out there knows what is causing these sustained spikes!!! Thanks guys
    sharonlind responded:
    First of all, make sure your b.p. machine is accurate. It can be double-checked in your doctor's office or at the local fire station. We found ours (a cuff type) was off. We have now purchased a portable professional one. Good luck Sharonlind
    dharma99 replied to ybonniy's response:
    Do yourself a favor and take this advise....
    Your condition may be linked to sleep apnea (OSA) which can complicate hypertension tremendously!!!
    Current research has linked sleep apnea (which if you have it gets worse as we get older) to sudden possibly dangerous spikes or changes in blood pressure. Some medications (yes, antihypertensives included, when dosages are increased) can worsen sleep apnea or trigger it, which in turn can do a number on your hypertension!
    I am including a medical research link for you to look it up and please print up a copy of this study for your doctor.
    I think you should be tested for pseudopheochromocytoma induced by OSA (Obstructive Sleep Apnea).
    Please don't let me scare you unnecessarily, I don't know your full symptomology or your medical history, but your doctor will know if you meet the criteria to be tested for this easily treatable disorder and stop the spikes and control your BP. Research has shown that once OSA is treated and controlled, many patients BP return to lower and manageable stable levels and require usually one antihypertensive to control. Again I am not saying that this is your problem, but it could be.
    OSA is under diagnosed and underestimated by many clinicians.
    THE LINK TO THE STUDY IS METCALFE&fulltext=PSEUDOPHEOCHROMOCYTOMA&searchid=1&FIRSTINDEX=0&sortspec=relevance&volume=89&resourcetype=HWCIT

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