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TTC with Endometriosis
An_242187 posted:
What are my chances of conceiving and carrying a child to term with possibility of advanced Endo?
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David K Walmer, MD, PhD responded:
Endometriosis is associated with infertility at all stages. With minimal endometriosis the cause of the infertility is not known. There is some evidence that the presence of endometrial cells in the peritoneal cavity leads to an inflammatory response that may not be an ideal environment for eggs. However, there are a number of theories that still need to be investigated. With advanced endometriosis, patients often develop pelvic adhesions that can decrease the amount of communication between the tubes and ovaries. Other patients develop large ovarian cysts and also limit the amount of ovarian surface that is accessible to the fallopian tubes. Infrequently, the distal fallopian tubes can become blocked. That said, as long as some eggs can find their way from the ovaries to the fallopian tubes it is possible for a woman to get pregnant. In vitro fertilization is an ideal therapy for women with advanced endometriosis because it bypasses the peritoneal cavity where the endometriosis resides. Once pregnant, women with advanced endometriosis often do very well. In fact, the high progesterone state of pregnancy is very similar to the hormonal states that we employ to treat endometriosis in women who are not pregnant. I hope this helps.

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