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Just adding to my last post
dselin68 posted:
called my Kidney doctor to talk with her about my latest bloodwork. She said my low levels were caused by consuming alcohol. The only problem is, I don't drink. She said it might be my liver, I'm really confused now. She said my bloodwork is really confusing, because my A/G ratio is at a 3.0, which is high. I don't know. Then she asked if I've been tested for HIV, which I have several times, and that's all negative. Can autoimmune disease cause all these issues with my bloodwork? Can I rely on just my bloodwork test? Should I let specialist that have only seen me once go off my bloodwork, when it's never consistent?
john-skpt responded:
I'm not a professional, but It would be good to look at a whole panel of blood work (not just the things that are flagged "high" or "low".) When docs look at blood numbers, they examine each value with respect to every other number. (For example: a low bicarbonate level with a low potassium means one thing, a low bicarb with a high potassium means something entirely different.)

The BUN:Creatinine ratio is fairly low, so that is less of a problem than if it were consistently over 20 (and that latter result might indicate narrowed renal arteries.)

The AST and ALT are liver enzymes, and these things definitely mean one thing when one is high than if the other one is high, or both of them are high or low. So I can't really guess about liver numbers without knowing exactly what ALL of them are, and without doing a lot of research on the different combos of these numbers.

The short answer to your big question is this: Yes, autoimmune conditions can produce the things that you have seen.

The unfortunate part of that is that it might take years of study to figure out exactly what is going wrong, and in many cases, the treatment is very harsh and fraught with its own complications: drugs that modify immune function are quite powerful, and often have unintended consequences (like increased cancer risk, other changes to blood and bone marrow, increased or more severe infections, just a whole list of potential problems.)
dselin68 replied to john-skpt's response:
Thanks John, you always seem to be able to explain things to where I can understand them. I guess I just don't know where to go from here. My PCP doc has been with me through the whole thing, and gets frustrated when I see a specialist, and they kind of pass it off after 1 test. I just wish there was more information out there about autoimmune disease and how your bloodwork is never normal, because you always, or at least I always have something going on with my body. My white blood cell counts are always high, in the 20 range, and my MCH is always high, around 36, and my FANA Staining patterns and Antinuclear Antibodies were both over 1:80 this last bloodwork, the time before they were equivical. I feel like my body is slowly dying, and there is nothing I can do, but ask questions. I just hope, someday soon, they will figure me out.
john-skpt replied to dselin68's response:
From what you have added, it DOES sound more and more like the immune system might be acting up. That doesn't absolutely mean a long term, chronic condition, it could also be environmental, workplace exposure to some element, it could be a lot of things.

I don't really know where to go but a rheumatologist, an allergist, or a hematologist might be one way to track down more info. Maybe your primary knows a good hematologist, etc to recommend.

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