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What would the sugestion as my Creatinine is 1.22
An_206733 posted:

This kiran i am 29 years old i am male and having ploysystic kindey whereas always i had blood presure since @ the age of 15 where as my preassure remains contastant @ 90/140 for which i dailly take medicine twice losar 50 and cardice 5..
last time when i checked my creatinine it was 1.05 in 09/2009 but where as now i have checked my creatinine is is showing 1.22 but where as referal level shows 0.7 to 1.22 .
is this really point ot worried? i m very much scared of it. definaetly i would sugest my nephrologis for but mean while can help any one help me by providing any good suggestion where by manully i can reduce my ceratinine level.

Really it would boost up my engery as well it would be really apriciated.

Advance Thanks
John-SKPT responded:
1.2 is not bad. (I just ignore the second decimal place; while tests may be able to calculate the number to that degree, it is truly insignificant; the tests just are not that accurate consistently.)

Unfortunately, with polycystic kidney disease, there really is not much that can be done to lower the creatinine number. As the cystic tissue very slowly displaces the functioning kidney tissue, the function will slowly decline. It may take a number of decades to reach the point where the patient needs dialysis or transplant, but in some cases things progress faster.

I suspect that the creatinine of 1.2 is not really making you feel all that bad right now. What I think may be lowering your energy level is the fact that your hematocrit and hemoglobin may be a little low. The hormone erythropoietin controls how many red blood cells are made by the bone marrow, and how many remain in the blood stream, and most of this hormone is created in the kidney.

There are synthetic versions of erythropoietin that can be injected by the doctor every few weeks (Procrit, Epogen are the US names, erythopoietin alpha is the chemical name, and Aranesp is a similar medicine). However, these genetically engineered drugs are very expensive, and--at least in the US--are not covered by medical insurance until the hematocrit has fallen quite low. There are some safety concerns as well. (Though I have taken them for 15 years with no bad side effects.) You can ask your doctor about them, and also find out what your hematocrit and hemoglobin are currently.

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