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    Osteo drug ups kidney failure risk
    Haylen_WebMD_Staff posted:
    Click link for full warning -targeted at patients who already suffer from kidney impairment.

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    1 of 1 found this helpful
    John-SKPT responded:
    There have been a number of serious problems reported with these 'expanded dose' osteoporosis drugs, those that are dosed by injection every few months or years.

    I suspect that most of these will get added black-box warnings, and some might even be withdrawn from the market.

    The older drugs like alendronate/Fosamax, those that are taken by mouth once a week, have a somewhat better safety record, though long term use still has some serious potential side effects.
    Haylen_WebMD_Staff replied to John-SKPT's response:
    John - I always feel that this kind of information should probably have been discovered BEFORE available to the public...never happy to post new warnings for a drug on the market...

    John-SKPT replied to Haylen_WebMD_Staff's response:
    Yes, we always feel let down when a new drug turns out to have bad side effects.

    But the newer FDA rules allow fast track approvals, which in the case of innovative lifesaving therapies might be a good thing. But the pharma companies take advantage of the newer rules to give them another few years to make bucks before their patents expire, even if a safer, more thoroughly tested drug is on the market.

    In many cases, the severe adverse events only show up after patients have used a drug for several years. Sort of 'we're damned if we do, and we're damned if we don't.'

    Spotlight: Member Stories

    My kidney experience includes many decades pre-dialysis, one year on hemo, an attempt at PD, and then transplant

    Helpful Tips

    I have a uti and severe kidney pain, Is this common?
    I have a uti and such bad kidney pain that I can hardly move, I cant bend down and it hurts more than I can explain. the pain comes and ... More
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    Report Problems With Your Medications to the FDA

    FDAYou are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.