Skip to content


Have you had a kidney transplant or are waiting for one? Then visit the Organ Transplant Community and the Diabetes and Kidney Community to share your experiences with other community members!

Are you newly diagnosed? Use the WebMD search engine to read articles like Understanding Kidney Disease.
Osteo drug ups kidney failure risk
Haylen_WebMD_Staff posted:
Click link for full warning -targeted at patients who already suffer from kidney impairment.

Was this Helpful?
1 of 1 found this helpful
John-SKPT responded:
There have been a number of serious problems reported with these 'expanded dose' osteoporosis drugs, those that are dosed by injection every few months or years.

I suspect that most of these will get added black-box warnings, and some might even be withdrawn from the market.

The older drugs like alendronate/Fosamax, those that are taken by mouth once a week, have a somewhat better safety record, though long term use still has some serious potential side effects.
Haylen_WebMD_Staff replied to John-SKPT's response:
John - I always feel that this kind of information should probably have been discovered BEFORE available to the public...never happy to post new warnings for a drug on the market...

John-SKPT replied to Haylen_WebMD_Staff's response:
Yes, we always feel let down when a new drug turns out to have bad side effects.

But the newer FDA rules allow fast track approvals, which in the case of innovative lifesaving therapies might be a good thing. But the pharma companies take advantage of the newer rules to give them another few years to make bucks before their patents expire, even if a safer, more thoroughly tested drug is on the market.

In many cases, the severe adverse events only show up after patients have used a drug for several years. Sort of 'we're damned if we do, and we're damned if we don't.'

Spotlight: Member Stories

Momma of 6 children, 3 beautiful girls ages, 20, 26, and 27 and 3 handsome boys ages, 21, 16, and 14. My 26 and 27 year old have finished college. My ...More

Helpful Tips

I have a uti and severe kidney pain, Is this common?
I have a uti and such bad kidney pain that I can hardly move, I cant bend down and it hurts more than I can explain. the pain comes and ... More
Was this Helpful?
0 of 0 found this helpful

Report Problems With Your Medications to the FDA

FDAYou are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.