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Knee staph infection - Help
char2research posted:
My brother in law had his knee replaced 3 years ago. Soon after the therapy completed and he was walking again, he got MRSA infection. They tried to clear it up with antibiotics but had to take it out and use a concrete spacer. He was on the pic-line for 4 months with antibiotics. Finally it was better and they put in a new knee replacement. He has been doing really well for about 2 years now, walking, golfing, etc. and recently had severe pain in the knee. Went to hospital and they found he had a staph infection. Doc went in and cleaned flushed out the knee. Brother in law is again on the pic-line antibiotic for 8 weeks. We are at week 5 and he had a big red spot on the knee. Went to Doc on Monday. Doc said will keep an eye on it, continue pic-line antibiotic. My question - has anyone else experienced this or heard about it happening twice??? We are all still young (early 50's) and he can't work (again), so looking for some possible alternatives to this treatment.
debidools responded:
My mother is going through the same thing with her hip replacements right now. They can't figure it out. Has your brother in law had any progress since you posted this? Ty
char2research replied to debidools's response:
No progress. Dr found him to have the infection thruout body and has now done the surgery and taken knee out. He has a metal brace from his ankle to his groin on his leg. No bending at all, pick line with heavy duty antibiotics, nurse 3x a week to change pick line and a diagnosis of 3 to 6 months before we know if the infection is gone. Also told he will not work at carpenter any more so go on permanent disability. Suggested to my sister to see another infectious disease specialist. that appointment is Thurs of this coming week. We are looking for answers as to why he keeps getting infected in the knee...
Any information is helpful. Thanks for answering.

Sorry to hear about your mom. Do yourself a favor and get the best infectious disease doctor you can find, one that is board certified and is a fellow - otherwise, this could be her in a couple of years...
pattieknee replied to char2research's response:
I had knee replaced 5 yrs ago with 'minor' infections. Then 3 yrs ago started having infections that required a new knee replacement after 6 wks of IV meds. 2 yrs ago I was ut on IV meds again for infection again. This past Oct. my knee was opened up, debrided etc. I was told the next time I get an infection, my knee would be fused. I have been on oral antibiotics for the past 2 yrs and looking for answers.
The latest solution is to remove the hardware, put in spacers & IV meds for 6-8 wks and do a calf muscle flap OR option 2 is to leave the spaces in for anther 6 wks to determine if the infection is truly gone or not. I am so confused & afraid to get another opinion & confuse me more. Have you heard anything like this?
char2research replied to pattieknee's response:
Just learned thru this discussion that someone else with similar infection problems had found thru additional doctors opinions that he is allergic to some of the metal in the replacement knee. Even though the allergic metal is only 3% - it is enough that he had major problems like us. My sister is now with a fantastic infectious disease specialist who is looking into the possibility of allergic reactions to some of the replacement knee components. You should research in this discussion and see others posts about infections and find a board certified, with a fellowship, infectious disease specialist. We are praying for an answer so our family and our lives can become a little less stressed.
friendlyguy55 replied to char2research's response:
Hello I feel for you and yes it could be a little of both, allergic to hardware and infection. My friend had a total knee replacement and later she got an infection and was in the hospital for 2 weeks and She is still having problems. I had a
total right knee replacement Oct. 2010 and My body rejected the hardware. My hardware had a metal that I was allergic to.
I would get rashes all over my body and severe itchiness all over my body. In Sept. 2012 I had another total knee replacement and so far I still get the itchiness all over my body,
but I done have the rashes anymore. Now my right knee stays swollen all the time and is always really tight and It is numb all the time and lots of pain. I have a doctor's Appt. next Wed.
Feb. 18 2014 to see the allergy doctor. If you are allergic to your hardware it could cause a infection in your body. My
friend's doctor says want you get an infection and you get better, the infection will always be in your body, it never goes
away and you will get better.Good luck

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