Includes Expert Content
Use of Imuran
An_243790 posted:
I have both Systemic and Discoid Lupus. I have been taking Imuran for approximately two years and it seems to be affecting my kidneys. Before taking Imuran I had not experienced any changes in my kidney. I wanted to know if this is just happending to me or if there are others experiencing this.

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Has anyone experienced a change in kidney function while taking Imuran? I heard that it can affect your liver instead of kidney but I have noticed a change in my kidney function according to tests performed at my doctors office.
  • Yes, I have experienced this.
  • No, I have not experienced this.
  • I have experienced problems regarding my liver not my kidneys.
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R Swamy Venuturupalli, MD, FACR responded:
Sorry to hear that you are having kidney issues. This is unfortunately a terrible symptom of lupus. It is most likely that the lupus is getting worse and needs to be treated more aggressively than just being treated with imuran. Please follow up carefully with your doctor and make sure that the kidney disease is controlled as soon as possible in order to prevent progression to kidney failure. It is very unlikely that the imuran is causing the kidney problems.
pamboyd31 replied to R Swamy Venuturupalli, MD, FACR's response:
Thank you so very much for your help.