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Question about Immune Complexes
jujubeee714 posted:
I have SLE. I have positive ANA's dsDNA, antismith and all of em on a direct ANA panel except for the histones.

However, on the titer I'm always negative.

I have had intermittent tests (and consistently for the past year and a half) Direct ANA Test Results that say "Unable to obtain results due to immune complex issues". It raises eyebrows but I don't know what it means. My new rheumie has vowed to find out for me. My last rheumie said my ANA's are too high for the titer to work on me and people like me fall through the cracks on a dx. If it wasn't for being a classic case with 10/11 clinical symptoms (from the ACR) and haven't the luck of the direct ANA and skin punch biopsies I might still not be dx'd. (Was dx'd in 2010)

Has anyone else EVER HAD results unobtainable reoccuring from the Direct ANA due to immune complexing issues. I have been through two different labs now and done on a stat basis. LabCorp and Quest. I also had a private lab who was interested in my antibodies do one and the lab guys said my blood looked like little pacmen were eating it up. Idk what this means. It is frustrating.

Thank you to anyone anywhere who can help me. I see my rheumatologist at the end of this month on a follow up and hopefully there will be more answers for me.
lupylisa44 responded:
I have no clue!!! Maybe Dr. V can answer this for you.

With love, with patience and with faith, we'll make our way.

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