Find Information About:

Drugs & Supplements

Get information and reviews on prescription drugs, over-the-counter medications, vitamins, and supplements. Search by name or medical condition.

Pill Identifier

Pill Identifier

Having trouble identifying your pills?

Enter the shape, color, or imprint of your prescription or OTC drug. Our pill identification tool will display pictures that you can compare to your pill.

Get Started

My Medicine

Save your medicine, check interactions, sign up for FDA alerts, create family profiles and more.

Get Started

WebMD Health Experts and Community

Talk to health experts and other people like you in WebMD's Communities. It's a safe forum where you can create or participate in support groups and discussions about health topics that interest you.

  • Second Opinion

    Second Opinion

    Read expert perspectives on popular health topics.

  • Community


    Connect with people like you, and get expert guidance on living a healthy life.

Got a health question? Get answers provided by leading organizations, doctors, and experts.

Get Answers

Sign up to receive WebMD's award-winning content delivered to your inbox.

Sign Up


All communities will be placed in read-only mode (you will be able to see and search for posts but not start or reply to discussions) as we conduct maintenance. We will make another announcement when posting is re-opened. Thank you for your continued support and patience, and if you have any further questions, please email

Yours in health,
WebMD Community Management

Includes Expert Content
Question for Dr. V
lupylisa44 posted:
My doctors are stumped and I could use your input. My lupus/nephritis is flaring. My serum creatine increased to 1.3, my urine protein is 2.3 g and my C3 has decreased. I have increased my cellcept to 2000mg and medrol 8mg bid.

My blood pressure is high and I seem to be allergic or sensitive to most BP meds ( Losartan, irbesaertan, lisinopril and now Tekturna) My question is: Do you know of any other meds that could lower my BP and help protect my kidneys?

With love, with patience and with faith, we'll make our way.
lupylisa44 responded:
Was just reading the information on Tekturna and in the Warnings it says " WARNINGS AND PRECAUTIONS: has been reported to cause exacerbation or activation of systemic lupus erythematosus.

Why on earth would a doctor prescribe medicine that would exacerbate lupus ,especially since my lupus was already active?
With love, with patience and with faith, we'll make our way.
R Swamy Venuturupalli, MD, FACR responded:

Dear Lupylisa,

I'm so sorry that things are not going great for you. I think you had reached out earlier with a similar question. If I remember correctly, your lupus nephritis was not responsive to cytoxan. In cases where the standard treatments are not working, we consider unapproved/ non-standard approaches.

There are numerous case reports that Rituximab might be of benefit in cases of lupus nephritis. As you may know, when Rituximab was studied in a controlled study, it failed to meet the primary end points. The trial design, where all patients were given high doses of steroids up front and the numbers of patients were not high enough to detect significant differences has been criticized extensively. This might explain why the drug did not meet the endpoints. Having said that many doctors in the lupus community, myself included, have had success in some patients with lupus using that drug. This might be an option for you to consider.

Additionally, we have been studying some medications for lupus nephritis including abatacept and we will know our preliminary data in the next month or so. A medication called epratizumab is being studied and Belimumab is also being studied in clinical trials for nephritis. Most clinical trials for nephritis require a recent renal biopsy, and I think that might be an issue for you given your past experience of bleeding after the procedure. However, depending on how bad your proteinurea is, there might be some trials that you could qualify for without a renal biopsy.

Hope that helps. Wishing you the best!
lupylisa44 replied to R Swamy Venuturupalli, MD, FACR's response:
Thank you!
With love, with patience and with faith, we'll make our way.

With Lupus

WebMD's Day2Night will help you develop personal coping strategies for living with lupus – at home,
at work, or with family
and friends.
Visit Lupus Day2Night

Helpful Tips

Music Video Tips on Managing Chronic Pain!
My newest music video, hope you guys like it! HUGS and ?, JJ "Never doubt that a small group of thoughtful, committed people can change the ... More
Was this Helpful?
1 of 1 found this helpful

Related Drug Reviews

  • Drug Name User Reviews

Report Problems With Your Medications to the FDA

FDAYou are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.