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Promising Early Results on Lupus Treatment
R Swamy Venuturupalli, MD, FACR posted:
This is an novel treatment strategy that involves blocking toll like receptors. There is good research to suggest that in Lupus Toll like receptors are inappropriately activated by anti-nuclear antibodies which are complexed with self RNA or DNA. Blocking Toll like receptors may help prevent the immune activation and resultant inflammatory response. In fact, there is good evidence that medications such as plaquenil, which have been in use for lupus for decades act via their effects on toll like receptors. This new generation of toll like receptor blockers (there are a few of these medications currently in clinical trials) promise to be better and potentially safer, which is why they are interesting. Of course, the information that is highlighted in this particular report is still very early in testing and it remains to be seen if the effects can be maintained in human trials.
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K2isKsquared responded:
Dr Venuturupalli,

Thanks so much for posting this!! It's nice to know someone is thinking of us and working toward a cure.


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