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Y Chromosome Deletion question
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KeltischWerWolf posted:
Hello My Name is Michael,

After almost 2 years of tryin to conceive with my wife, i get my bloodtests back it states i have Y Chromosome Deletion, passed on by my father who had 2 children, for a long time after we made love and ejaculated into her, and odor would present itself, now im no dummy i am medically trained so i do know that is normal with sperm decay, but right before i went for my first semenalysis, i started on bike rides to help me lose weight, had a different seat to help with compression but it hurt after i got done with my rides, now i think i created a blockage, and went through all these tests except for an ultrasound, but the current doctor is to expensive and out of our CIGNA Network Coverage, was wondering if anyone can recomend a Male Reproductive Urologist in Orlando, not including Dr. Michael Witt, he is my current one. I appreciate any help that is given thanks.
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AmyAALC responded:
Michael I'll check with the urologists in my office to see if they have any recommendations in the Orlando area. Baylor College of Medicine has one of the leading programs in male infertility and focus on Y chromosome microdeletions.

The odor you mentioned is of concern. A strong odor is not normal following intercourse. It is possible that one of the two or both of you have an infection. Do you notice this odor only after intercourse or also after masturbation? Sperm can live up to 5 days in the female reproductive tract and these small cells should not release any kind of odor from decay.

Bike riding can cause pressure on the never endings and blood vessels for both men and women in the genital area. This can lead to lowered fertility and ED. We recommend a no-nose seat. The riding is not associated with obstruction or blockage of the male reproductive system.

I think the biggest concern is the Y-chromosome deletion. Pregnancies have been achieved with sperm from patients with Y chromosome deletions. The female offspring from these males should be normal, however, the male offspring are likely to be infertile, as they will inherit the defective Y chromosome from their fathers. In your situation your father likely had the deletion and you being the male offspring also have the deletion and being infertile. Are you azoospermic - no sperm seen in the ejaculate? There are different levels of Y chromosome deletions causing some men to have very low sperm production and others having no sperm production. If you are exploring the options of having biological children remember this is something that you will pass to your son so seek the guidance of a genetic counselor is always best.

Your situation is very interesting and thanks for sharing. The frequency of Y chromosome deletions in azoospermic men range from 5-15%. The frequency of deletions on the Y chromosome have the largest impact on if any sperm can be found in Y chromosome deletion males.

Amy Perkins, MS, TS
Laboratory Supervisor
Arizona Andrology Laboratory & Cryobank
International Center for Vasectomy Reversal


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