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Multi-vitamins during Menopause
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kellyjgchamp posted:
I am 34-years-old and had a hysterectomy last year. I also have the BRCA-2 gene and therefore, cannot take hormones. I just finished a bottle of multi-vitamins that I've had and need to get a new bottle. Should I be taking a special multi-vitamin because of my early menopause?
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sjb05151956 responded:
I've come across this before - women who say they can't take HRT after ovary removal because they're BRCA1 or BRCA2 . But the following indicates that HRT (at least in the short-term) may be safe after ovary removal -
http://www.ncbi.nlm.nih.gov/pubmed/16219936
http://ww5.komen.org/KomenNewsArticle.aspx?id=19327353042
"For women with BRCA1 or BRCA2 gene mutations, use of hormone replacement therapy after preventive removal of the ovaries and fallopian tubes does not appear to increase the risk of breast cancer. These results were presented at the 2011 annual meeting of the American Society of Clinical Oncology."

This study http://www.ncbi.nlm.nih.gov/pubmed/20226402 says that "Observational studies show that estrogen deficiency, resulting from premenopausal or postmenopausal oophorectomy, is associated with higher risks of coronary artery disease, stroke, hip fracture, Parkinsonism, dementia, cognitive impairment, depression, and anxiety."

One must weigh ALL the risks and benefits of estrogen replacement versus estrogen deficiency. And of course, quality of life should also be considered.


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