Skip to content


    Exciting News for WebMD Members!

    We've been busy behind the scenes building new message boards for you. You'll have new and easier ways to find messages, connect with others, and share your stories.

    And, this will all be available on your smartphone or other mobile device!

    What Do You Need to Do?

    The message board you're used to will be closing in the coming weeks. While many of your boards will be making the move to our new home, your posts will not. Want to keep a discussion going? Save posts you want to continue (this includes your member profile story), so that you can re-post them in the new message boards.

    Keep an eye here and on your email inbox, we'll be back in touch soon to give you all the information you need!

    Yours in health,
    WebMD Message Boards Management

    Includes Expert Content
    Can I go on HRTs with Triple Negative Breast Cancer Diagnosis?
    survivor0805 posted:
    I am 49 years old and had breast cancer 8 years ago. I am now having eextreme hot flashes, severe depression and very little sleep. Due to my cancer dagnosis, I have not gone on any hormone replacement therapy but the over the counter medications do not seem to work anymore...I have tried Chinese Meds, Black Cohosh, and I-Cool. Antidepresents were keeping me awake. Since my cancer was not hormone receptive, does anyone know the risk if I go on some type of hormone replacement therapy??
    Mary Jane Minkin, MD responded:
    Dear Survivor0805,
    A couple of easy suggestions. You mentioned that you had tried black cohosh; have you tried the specific brand of Remifemin? Quality of some black cohosh products are quite variable; Remifemin is a standardized product-it still might not work, but you'll know exactly what you are getting. One option coming out this fall is a very low dose of paroxetine; it will be called Brisdelle, and seems to have fewer of the antidepresssant side effects, because of its dose, but it does have hot flash efficacy. I do think that you may well be a good candidate for HT, given that you are many years out (that's terrific) from a triple negative tumor. Is your oncologist OK with you doing some low dose HT? if (s)he is, and your gynecologist is OK, too-sounds totally reasonable to me. If your oncologist is fine with it, and your gyn is not, go to the North American Menopause Society's website,, for a list of menopause folks near you, to discuss this situation.
    Good luck,
    Mary Jane

    Featuring Experts

    Mary Jane Minkin, MD, is a nationally recognized obstetrician gynecologist, with a special interest in menopause. Dr. Minkin is clinical professor of ...More

    Helpful Tips

    Hot flash & Night sweat relief
    I am 51 and started perimenopause 6 years ago. I experience hot flashes and night sweats heavily every two weeks - the time I usually ... More
    Was this Helpful?
    1 of 1 found this helpful

    Related Drug Reviews

    • Drug Name User Reviews

    Report Problems With Your Medications to the FDA

    FDAYou are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

    For more information, visit the North American Menopause Society website