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    HRT for premature menopause
    An_257584 posted:
    I am 34 years old and I was diagnosed with premature menopause last year and was given a HRT cycloproginova pills. I finished my first round and after 6 days I am still not getting cycle. Should I continue with taking pills of cyclopr. even if I don't get menstrual cycle?
    In 2010 I had removed endometriosis, cysts on both ovaries.
    Mary Jane Minkin, MD responded:
    Dear An257584,
    I had to go check exactly what was in cycloproginova; it is a good medication, which is basically cyclical estrogen and estrogen plus progestin, in the second half of the cycle. (It is a combination that is not available in the US, but is available in Europe). In general, I would just reassure you that it is indeed not uncommon with low dose estrogen replacement therapy to not get a withdrawal bleed; so in general I would tell my patients just to start the next cycle. My slight hesitancy is that it is remotely possible for ovaries in this situation to "wake up"-ie, is there any possibility you could be pregnant-have you been sexually active? I would just (because of my very cautious nature)-suggest that you check in with your gynecologist-
    Good luck,
    Mary Jane
    An_257584 replied to Mary Jane Minkin, MD's response:
    Thank you very much for your reply. Well I was sex. active only one time, like 3 weeks ago. I will def. check if by any chance I am pregnant, but I doubt it. I don't really understand what did you mean by: My slight hesitancy is that it is remotely possible for ovaries in this situation to "wake up". ?
    Unfortunately I was also diagnosed with POF.

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