Hi, it sounds like Hemiplegic Migraine. I am a 4th generation sufferer of Familial Hemiplegic Migraine. I was not diagnosed till I was 37 even though I had symptoms since I was born. The best thing to do is find a Headache Clinic either go there or have them recommend Neurologists and Pain Specialists in your area. My Pain Specialist was who figured it out not any of the Neurologists. You need to start a headache diary and a food diary, they will help with finding triggers and what therapy is best for your wife's individual needs. I am not a doctor but I can try my best to help you, even listening helps.
Good luck!

How long has she been taking the Topamax and verapamil? It may take time to work, you need to take it at least a month to see if it helps her. It also sounds like borderline cluster headache.

Since 3/2/12 she has had 27 attacks. They last from as short as 20 minutes to as long as 3 hours. each attack brings her pain level to 10 . Her doctor has increased her Topamax to 200mg a day, plus Reglan and two Aspirin at start. The doctor says she has complex migraine. She has been taking Verapimil and topamax since 10/11 when all of this started. Just yesterday she had three attacks. We can find no triggers for these events since they occur at many different times and last different times.

How is your wife doing? I hope a little better. Please check out these links for some insight on which way to seek care that best suits her. I again encourage you to keep a headache and food diary to help find triggers. The first one explains a lot in regards to your wife's care. Good luck.
http://migraine.com/blog/living-with-migraine/complex-complicated-migraine/

http://www.webmd.com/migraines-headaches/guide/headache-diary

http://www.webmd.com/migraines-headaches/avoiding-migraine-triggers

Thanks for your response. My wife is the same as before. She has three attacks a day. We are keeping a log of these and giving them to her doctor. Her last doctor visit was interesting. He showed me how to stop her hand tremor. By slowly moving her arm back and forth, I am able to find a point which stops the tremor. As for the triggers, we find nothing. In the last two days, she has had an attack while she was asleep. She wakes with the worst headache.

Are the preventatives helping her? Also part of her headache symptoms sound something like clusters, which are behind the eye.

Her current preventatives don't seem to be working. This past sunday I had to take her to the ER. The right side of her face is flat. When she attempts a smile, only the left side moves and is weak. She had two attacks sunday morning when I noticed. While in the ER, she had 7 more attacks that were 20 minutes apart or less. Her head pain was maxed out. She was vomiting several times both at home and in the ER. She was admitted overnight. She is home now and her attacks have increased to 5 or more in a day. Had an appointment with her migraine doctor yesterday. He says she is doing fine, no medication change and will not see him again for 3 weeks.
I can't understand if she has more attacks and much worse head pain how she could be doing fine. Sometime I can stop her hand tremor, but have several times I can't feel the feedback I usually do. One drug that she should not take, gabapentin, caused her to try and slit her wrist. Her Primary told her to not ever take that drug again. Then the doctor at the hospital puts her back on it. I think I am not going to allow this drug for her. He also put her on Naproxin.
Something new in the last two weeks, her memory is not right. She can not remember something 10 minutes afterwords or finding the words she wants to say.
I am so confused by all of this and it doesn't seem to be letting up.
Thanks to all who have responded.

I failed to mention that her migraine doctor said she has Complex Migraines, while the hospital doctor says Hemiplegic.

Sorry I haven't been able to reply in a while. Your wife's "Migraine Doctor" sounds very off the mark. I attached the links for you to read in regards to "complex migraine" - There is no such thing! Complex migraine is not any where in accepted medical literature.http://migraine.com/blog/living-with-migraine/complex-complicated-migraine/
I recommend you see other doctors as you already have a different opinion from the Hospital Doctor, and that Doctor agrees with your assessment of Hemiplegic Migraine. As far as the medicine goes take your wife off the Gabapentin tell your pharmacy and all medical staff involved with your wife that she is allergic to it!!!! You don't need her to try and slit her wrist again. You are your wife's advocate in this and have every right to tell the doctor NO, please prescribe something else.
The memory loss is part of the Migraine try not to worry about it too much I have been living with it for a longtime. I have days when I can't even speak properly it feels like my tongue swelled up or I was at the dentist. It really becomes troublesome when I read or someone is speaking to me and the information sounds "backwards" as if my understanding has become Dyslexic and I can't make sense of the words. Not finding words to say - don't laugh but I tell people all the time I'll remember tomorrow and it can take that long for me to remember a word. I will send you links to Headache clinics.
I really hope she has less pain and attacks.

Thanks for your reply. I did read the links you sent and ask the doctor what type she has and his reply was, complex. He then told me that complex is not listed as a type in medical terms. He says that since she has symptoms of several types he can't exclude some types. I have thought of seeing another doctor, but this doctor is the most recommended here.
I stopped the Gabapentin as soon as I found out. Some doctors have ask why she is allergic to that drug and when explained, they say it is not an allergic reaction because it is not indicated by a rash or breathing problems. It is clearly indicated in her records that that drug causes psychosis.
My wife continues to have these attacks up to 6 times a day. Now they are coming back to back and everyday is different in length and time. She now says her vision in her right eye is cloudy and blurred during the attack. Her pain is always max during the attacks and only abates after an hour or more. My log of these attacks now looks like a book. She will see the doctor this week, 3 weeks since last visit.

Change drs, it seems your dr isn't helping you.

No new doctor yet. Most nurses and other doctors say the one she is seeing is the best. have been to the ER twice this week. One attack completely blanked her memory. She couldn't smile. All test were negative. She has been on one new medication, which causes her to sleep a lot. She continues the 7 or 8 attacks a day. Can not find a trigger. One thing that is odd is that she doesn't have attacks in the evening. Most of the time she is asleep by 6:30pm. Morning attacks run together, this morning she has had 4 since waking at 5:00am.

Maybe try putting ice around her head. get techni-ice, cut it into strips, wrap them in bandanas and freeze them. Then take them out and wrap them around your head.