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never ending headaches
djkaz posted:
got some info for you. Look up PFO. patent foramen ovale, a heart condition.
Timothy Collins, MD responded:
The only placebo/sham controlled trial published so far found no effect at all on migraine with PFO closure.

This is the only controlled trial published. ALL the other published information is uncontrolled series of patients, mostly selected for presence of a PFO. In this study, they selected patients based on their migraines, looked for a PFO, and closed the PFO in 2/3 of the patients (1/3 of patients had a cardiac cath, but did not have the PFO closed). The patients and treating MD did not know who had a closed PFO. (this was a blinded study)