My sister was diagnosed with MS in 1995. She has been on every form of therapy but has had adverse reactions, last hope was Tysabri. After being on it 1 year she had a blood test and found out last week she has the JC virus. Evidently this can lead to the PML virus. We are desperately seeking information on these viruses. She has been told they could "wash" her blood to try to prevent the PML virus. We would like to know the chances of her getting the JC virus without the washing and if she should discontinue her treatments. Her MS physician's office does not seem to be a lot of help in giving her information. I am 3 states away and cannot go to appointments with her and her husband, they don't ask many questions. Anyone have any information on these viruses?
JC virus is not that uncommon and many of us have been exposed and would have positive blood tests for this virus. Although having a positive blood test may be a risk factor for PML, it does not mean that she will get this disease. The risk for PML at 2 years is 1 in 1000. If her MS physician is not able to help, then perhaps a different MS physician might be more helpful.
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