Skip to content


    Attention All WebMD Community Members:

    These message boards are closed to posting. Please head on over to our new WebMD Message Boards to check out and participate in the great conversations taking place:

    Your new WebMD Message Boards are now open!

    Making the move is as easy as 1-2-3.

    1. Head over to this page:

    2. Choose the tag from the drop-down menu that clicks most with you (and add it to any posts you create so others can easily find and sort through posts)

    3. Start posting

    Have questions? Email us anytime at

    For Women who have MS--- Do you notice that your MS gets worse before or during your period?
    gorgeouslytired posted:
    Hello!!! So, I asked my neuro about this and she said she's never heard anyone report what I had said... I feel as if a week before my period, my MS symptoms get a lot worse (weakness, fatigue, brain fog, some minor numbness, depression). I've spoken to my neuro and psychiatrist about having possible PMDD (which is like PMS x10). They wanted to prescribe me prozac for this but I decided not to since I'm already on Copaxone and trying vitamins and homeopathic stuff first. I've noticed some months are a lot worse than others, and I also noticed that when I drink alcohol around this time, it makes my PMS a lot worse... Is this weird?

    Has anyone else experienced this? Or noticed their symptoms get worse around their period?
    hackwriter responded:
    Dear gorgeous,

    I get very fatigued prior to my period--but I always did, even before I developed MS, only now it's even worse. I sleep longer hours and want to take naps during PMS. This makes sense for me since I battle fatigue and weakness every day, and I already have a history of increased sleepiness during PMS.

    My theory is that the hormone fluctuation magnifies our MS symptoms temporarily, just as hot, humid weather will temporarily worsen our symptoms. We are very sensitive to environmental changes, both inner and outer.

    That's my two cents.


    Featuring Experts

    Stephanie knows multiple sclerosis as a patient and as a nurse. Stephanie was diagnosed with multiple sclerosis in 2013. Shortly after being diagnosed...More

    Helpful Tips

    Reliv does work
    I thought Reliv was a hoax too. But it's not. You need to take it regularly and consistently and it proves miracles. My mom was diagnosed ... More
    Was this Helpful?
    1 of 1 found this helpful

    Related Drug Reviews

    • Drug Name User Reviews

    Report Problems With Your Medications to the FDA

    FDAYou are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.